CAS 42924-53-8
:Nabumetone
Description:
Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for the treatment of osteoarthritis and rheumatoid arthritis. It is characterized by its analgesic and anti-inflammatory properties, which are attributed to its ability to inhibit cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins involved in inflammation and pain. Nabumetone is unique among NSAIDs as it is a prodrug, meaning it is metabolized in the liver to its active form, 6-methoxy-2-naphthylacetic acid. This metabolic conversion allows for a potentially lower incidence of gastrointestinal side effects compared to traditional NSAIDs. The substance is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include gastrointestinal discomfort, headache, and dizziness, while more serious risks involve cardiovascular and renal complications. As with all NSAIDs, it is important for patients to use nabumetone under medical supervision, particularly those with pre-existing health conditions.
Formula:C15H16O2
InChI:InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3
InChI key:InChIKey=BLXXJMDCKKHMKV-UHFFFAOYSA-N
SMILES:C(CC(C)=O)C1=CC2=C(C=C(OC)C=C2)C=C1
Synonyms:- 1-(2′-Methoxynaphth-6′-yl)butan-3-one
- 2-Butanone, 4-(6-methoxy-2-naphthalenyl)-
- 4-(6-Methoxy-2-naphthalenyl)-2-butanone
- 4-(6-Methoxy-2-naphthyl)-2-butanone
- 4-(6-Methoxynaphthalen-2-Yl)Butan-2-One
- Arthaxan
- Balmox
- Brl 14777
- Consolan
- Coxalgan
- Gambaran
- Methyl 3-(6-Methoxynaphthalen-2-Yl)Propanoate
- Nabucox
- Nabugesic 500
- Nabumeton
- Nabuser
- Nabuton VP
- Relafen
- Relif
- Relifen
- Relifex
- Rodanol
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 18 products.
Nabumetone
CAS:<p>Anti-inflammatory, anti-bacterial. A non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original </p>Formula:C15H16O2Molecular weight:228.29Nabumetone
CAS:NabumetoneFormula:C15H16O2Purity:99.8%Color and Shape:Off White SolidMolecular weight:228.11503Nabumetone
CAS:<p>Ketone-phenols and ketones with other oxygen function</p>Formula:C15H16O2Color and Shape:PowderMolecular weight:228.11503Nabumetone
CAS:<p>Nabumetone (BRL14777)(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.</p>Formula:C15H16O2Purity:97.59% - 99.61%Color and Shape:White /Almost White Crystalline PowderMolecular weight:228.29Nabumetone
CAS:Formula:C15H16O2Purity:≥ 98.0% (anhydrous basis)Color and Shape:White to almost white crystalline powderMolecular weight:228.294-(6-Methoxynaphthalen-2-Yl)Butan-2-One
CAS:<p>4-(6-Methoxynaphthalen-2-Yl)Butan-2-One</p>Purity:98%Molecular weight:228.29g/molNabumetone
CAS:Controlled Product<p>Applications Nabumetone is an anti-inflammatory and antibacterial agent (1). A non-steroidal anti-inflammatory prodrug used for treatment of inflammatory and degenerative rheumatic diseases.<br>References (1) Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Formula:C15H16O2Color and Shape:NeatMolecular weight:228.29Nabumetone - Bio-X ™
CAS:<p>Nabumetone is a non-steroidal anti-inflammatory drug that is used in the treatment of osteoarthritis and rheumatoid arthritis. This drug is also a cyclooxygenase inhibitor and works by inhibiting this enzyme so that pain and inflammation is reduced.</p>Formula:C15H16O2Purity:Min. 95%Color and Shape:PowderMolecular weight:228.29 g/molNabumetone
CAS:<p>COX-2 inhibitor; nonsteroidal anti-inflammatory drug</p>Formula:C15H16O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:228.29 g/mol4-(6-Methoxynaphthalen-2-yl)butan-2-one
CAS:Formula:C15H16O2Purity:98%Color and Shape:SolidMolecular weight:228.291
