CAS 4295-08-3

2-chloro-4-ethoxyquinoline

Description:

2-Chloro-4-ethoxyquinoline is an organic compound characterized by its quinoline structure, which consists of a fused benzene and pyridine ring. The presence of a chlorine atom at the second position and an ethoxy group at the fourth position of the quinoline ring significantly influences its chemical properties and reactivity. This compound typically appears as a yellow to brown solid and is sparingly soluble in water but more soluble in organic solvents such as ethanol and dichloromethane. It may exhibit biological activity, making it of interest in medicinal chemistry and pharmacology. The chlorine substituent can enhance the compound's lipophilicity, potentially affecting its interaction with biological targets. Additionally, 2-chloro-4-ethoxyquinoline can undergo various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions, due to the presence of the reactive functional groups. Safety data should be consulted for handling and storage, as with many halogenated compounds, it may pose health risks if not managed properly.

Formula: C₁₁H₁₀ClNO

InChI: InChI=1/C11H10ClNO/c1-2-14-10-7-11(12)13-9-6-4-3-5-8(9)10/h3-7H,2H2,1H3

SMILES: CCOc1cc(Cl)nc2ccccc12

Synonyms:

• Quinoline, 2-Chloro-4-Ethoxy-
• 2-Chloro-4-ethoxyquinoline

2-Chloro-4-ethoxyquinoline

CAS: 4295-08-3

Formula: C₁₁H₁₀ClNO

Color and Shape: Solid

Molecular weight: 207.6562

Ref: IN-DA00C9XM

2-Chloro-4-ethoxyquinoline

Controlled Product

CAS: 4295-08-3

Applications Quinoline derivative used in the preparation of compounds with anticonvulsant activity as well as compounds with potent antibacterial activity against gram-positive pathogens.
References Guo, L. et al.: Eur. J. Med. Chem., 44, 954 (2009); Jarvest, R.L. et al.: J. Med. Chem., 45, 1959 (2002);

Formula: C₁₁H₁₀ClNO

Color and Shape: Neat

Molecular weight: 207.66

Ref: TR-C365730