CAS 4295-55-0

2-[(2,3-Dichlorophenyl)amino]benzoic acid

Description:

2-[(2,3-Dichlorophenyl)amino]benzoic acid, also known by its CAS number 4295-55-0, is an organic compound characterized by its aromatic structure, which includes a benzoic acid moiety and a dichlorophenyl group. This compound features a carboxylic acid functional group (-COOH) that contributes to its acidity and potential for forming salts and esters. The presence of the dichlorophenyl group indicates that it has two chlorine atoms substituted on the phenyl ring, which can influence its reactivity, solubility, and biological activity. Typically, compounds of this nature may exhibit properties such as moderate to high lipophilicity due to their aromatic nature, and they may participate in hydrogen bonding due to the carboxylic acid group. Additionally, the dichlorophenyl substitution can enhance the compound's stability and alter its interaction with biological systems, making it of interest in pharmaceutical research. Overall, 2-[(2,3-Dichlorophenyl)amino]benzoic acid is a compound with potential applications in medicinal chemistry and material science.

Formula: C₁₃H₉Cl₂NO₂

InChI: InChI=1/C13H9Cl2NO2/c14-9-5-3-7-11(12(9)15)16-10-6-2-1-4-8(10)13(17)18/h1-7,16H,(H,17,18)

InChI key: InChIKey=JONFYSWOLCTYFK-UHFFFAOYSA-N

SMILES: N(C1=C(C(O)=O)C=CC=C1)C2=C(Cl)C(Cl)=CC=C2

Synonyms:

• Benzoic acid, 2-[(2,3-dichlorophenyl)amino]-
• 2-[(3-CHLOROPHENYL)AMINO]BENZOIC ACID
• N-(3-CHLOROPHENYL)ANTHRANILIC ACID
• Clofenamic acid
• Anthranilic acid, N-(2,3-dichlorophenyl)-
• clofenamic acid
• 2-[(2,3-Dichlorophenyl)amino]benzoic acid
• 2-(3-CHLOROANILINO)BENZOIC ACID
• N-(2,3-Dichlorophenyl)anthranilic acid
• 2-[(2,3-dichlorophenyl)amino]benzoic acid
• 2-(2,3-Dichloroanilino)benzoic acid
• CLOFENAMIC ACID (BP) [N-(2,3-DICHLOROPHENYL)ANTHRANILIC ACID]
• N-2,3-dichlorophenylanthranilic acid
• ACIDUMCLOFENAMIC
• Chlofenamic acid

2-[(2,3-Dichlorophenyl)amino]benzoic acid

CAS: 4295-55-0

2-[(2,3-Dichlorophenyl)amino]benzoic acid is a nonsteroidal anti-inflammatory drug that binds to the receptor for prostaglandin E2. It has been shown to have anti-inflammatory and analgesic effects in animal models of inflammatory bowel disease and microbial infection. 2-[(2,3-Dichlorophenyl)amino]benzoic acid inhibits the release of inflammatory mediators such as leukotrienes (LTs), prostaglandins, histamine, and cytokines from mast cells and eosinophils. It also inhibits the production of proinflammatory cytokines by macrophages and T lymphocytes. This drug can be used in treatment of autoimmune diseases because it blocks the action of COX enzymes that produce prostaglandins involved in inflammation. 2-[(2,3-Dichlorophenyl)amino]benzoic acid has been shown to inhibit water vapor

Formula: C₁₃H₉Cl₂NO₂

Purity: Min. 95%

Molecular weight: 282.12 g/mol

Ref: 3D-EAA29555