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CAS 4299-60-9

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Sulfisoxazole diolamine

Description:
Sulfisoxazole diolamine is a sulfonamide antibiotic that belongs to the class of sulfa drugs, which are known for their bacteriostatic properties. It is characterized by its ability to inhibit bacterial growth by interfering with the synthesis of folic acid, a vital nutrient for bacteria. The compound typically appears as a white to off-white crystalline powder and is soluble in water, which facilitates its use in various pharmaceutical formulations. Sulfisoxazole diolamine is often employed in the treatment of urinary tract infections and other bacterial infections due to its effectiveness against a range of gram-positive and gram-negative bacteria. Its mechanism of action involves competitive inhibition of the enzyme dihydropteroate synthase, which is crucial in the bacterial folate synthesis pathway. While generally well-tolerated, it may cause side effects in some individuals, including allergic reactions or gastrointestinal disturbances. As with all antibiotics, appropriate usage is essential to prevent the development of antibiotic resistance.
Formula:C11H13N3O3S·C4H11NO2
InChI:InChI=1S/C11H13N3O3S.C4H11NO2/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10;6-3-1-5-2-4-7/h3-6,14H,12H2,1-2H3;5-7H,1-4H2
InChI key:InChIKey=FEPTXVIRMZIGFY-UHFFFAOYSA-N
SMILES:S(NC1=C(C)C(C)=NO1)(=O)(=O)C2=CC=C(N)C=C2.N(CCO)CCO
Synonyms:
  • N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide compound with 2,2′-iminodiethanol (1:1)
  • Sulfanilamide, N1-(3,4-dimethyl-5-isoxazolyl)-, compd. with 2,2′-iminodiethanol (1:1)
  • Ethanol, 2,2′-iminobis-, compd. with 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide (1:1)
  • Benzenesulfonamide, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)-, compd. with 2,2′-iminobis[ethanol] (1:1)
  • Ethanol, 2,2′-iminodi-, compd. with N1-(3,4-dimethyl-5-isoxazolyl)sulfanilamide (1:1)
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