CAS 4302-95-8

N-[(1R,2R)-2-[4-(Aminosulfonyl)phenyl]-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloroacetamide

Description:

N-[(1R,2R)-2-[4-(Aminosulfonyl)phenyl]-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloroacetamide, with CAS number 4302-95-8, is a chemical compound characterized by its complex structure, which includes a dichloroacetamide moiety and a sulfonamide group. This compound typically exhibits properties associated with both amides and sulfonamides, such as potential solubility in polar solvents and the ability to form hydrogen bonds due to the presence of hydroxyl and amine functional groups. It may also demonstrate biological activity, particularly in pharmaceutical applications, given its structural features that resemble those of known drug candidates. The presence of the dichloroacetyl group suggests potential reactivity, which could be relevant in synthetic chemistry or medicinal chemistry contexts. Additionally, the stereochemistry indicated by the (1R,2R) configuration may influence its biological interactions and pharmacokinetics. Overall, this compound's unique characteristics make it of interest in various fields, including medicinal chemistry and drug development.

Formula: C₁₁H₁₄Cl₂N₂O₅S

InChI: InChI=1S/C11H14Cl2N2O5S/c12-10(13)11(18)15-8(5-16)9(17)6-1-3-7(4-2-6)21(14,19)20/h1-4,8-10,16-17H,5H2,(H,15,18)(H2,14,19,20)/t8-,9-/m1/s1

InChI key: InChIKey=HODRFAVLXIFVTR-RKDXNWHRSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CO)(O)C1=CC=C(S(N)(=O)=O)C=C1

Synonyms:

• 4302-95-8
• <span class="text-smallcaps">D</span>-threo-(-)-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-sulfamoylphenethyl]acetamide
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-sulfamoylphenethyl]-, <span class="text-smallcaps">D</span>-threo-(-)-
• Acetamide, N-[(1R,2R)-2-[4-(aminosulfonyl)phenyl]-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloro-
• Acetamide, N-[2-[4-(aminosulfonyl)phenyl]-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloro-, [R-(R*,R*)]-
• Amp-3
• D-Amp-3
• D-threo-(-)-2,2-Dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-sulfamoylphenethyl]acetamide
• D-threo-1-(p-Sulfamoylphenyl)-2-(2',2'-dichloroacetamido)-1,3-propanediol
• N-[(1R,2R)-2-[4-(Aminosulfonyl)phenyl]-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloroacetamide
• Tevenel
• 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-sulfamoylphenyl)propan-2-yl]acetamide

Tevenel

CAS: 4302-95-8

Formula: C₁₁H₁₄Cl₂N₂O₅S

Molecular weight: 357.21

Ref: 4Z-T-217001