CAS 4313-73-9

N-cbz-phe-leu

Description:

N-Cbz-Phe-Leu, also known as N-carbobenzyloxy-L-phenylalanine-L-leucine, is a dipeptide derivative characterized by its structure, which includes a carbobenzyloxy (Cbz) protecting group on the phenylalanine (Phe) residue. This compound is typically utilized in peptide synthesis and research due to its stability and ability to protect the amino group of phenylalanine during chemical reactions. The presence of the leucine (Leu) residue contributes to its hydrophobic characteristics, influencing its solubility and interaction with other molecules. N-Cbz-Phe-Leu is often employed in the development of pharmaceuticals and in the study of protein interactions. Its CAS number, 4313-73-9, allows for easy identification in chemical databases. The compound is generally handled with standard laboratory safety precautions, as with many organic compounds, and its properties can vary based on the specific conditions of use, such as solvent and temperature.

Formula: C₂₃H₂₈N₂O₅

InChI: InChI=1/C23H28N2O5/c1-16(2)13-20(22(27)28)24-21(26)19(14-17-9-5-3-6-10-17)25-23(29)30-15-18-11-7-4-8-12-18/h3-12,16,19-20H,13-15H2,1-2H3,(H,24,26)(H,25,29)(H,27,28)

SMILES: CC(C)CC(C(=O)O)N=C(C(Cc1ccccc1)N=C(O)OCc1ccccc1)O

Synonyms:

• Z-Phe-Leu-OH
• N-[(benzyloxy)carbonyl]phenylalanylleucine

Z-Phe-Leu-OH

CAS: 4313-73-9

A good substrate for carboxypeptidase Y, the Streptomyces griseus carboxypeptidase, and the membrane-associated carboxypeptidase ysc-lambda.

Formula: C₂₃H₂₈N₂O₅

Purity: 99.9%

Color and Shape: White Powder

Molecular weight: 412.49

Ref: 01-4000487

Z-Phe-Leu-OH

CAS: 4313-73-9

Formula: C₂₃H₂₈N₂O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 412.4788

Ref: IN-DA00D9SS

Z-Phe-Leu-Oh

CAS: 4313-73-9

Z-Phe-Leu-Oh

Purity: 98%

Molecular weight: 412.48g/mol

Ref: 54-OR1029531

Z-Phe-Leu-OH

CAS: 4313-73-9

Purity: 97%

Molecular weight: 412.2

Ref: 10-F556406

Z-Phe-Leu-OH

CAS: 4313-73-9

Z-Phe-Leu-OH is a protease inhibitor that belongs to the group of peptidyl-protease inhibitors. It inhibits the activity of a wide range of proteases and is specifically active against carboxypeptidases A and B. Z-Phe-Leu-OH has been shown to be specific for these enzymes, with no inhibitory activity against other proteases such as aminopeptidases, serine proteases, or metalloproteases. The amino acid composition of this protease inhibitor is different from other inhibitors that have been studied in detail. This agent was found to be more effective than phenylmethylsulfonyl fluoride (PMSF) at inhibiting carboxypeptidase A and B.
Z-Phe-Leu-OH has been shown to be an acidic compound with a pKa of 5.5; however, it does not react with chloromethyl ketone

Formula: C₂₃H₂₈N₂O₅

Purity: Min. 95%

Molecular weight: 412.48 g/mol

Ref: 3D-FP110846