CAS 43168-51-0

Minocycline EP Impurity A (4-epi Minocycline)

CAS: 43168-51-0

Formula: C₂₃H₂₇N₃O₇

Molecular weight: 457.48

Ref: 4Z-M-3419

4-Epi Minocycline (>80%, contains unidentified salts)

CAS: 43168-51-0

Impurity Minocycline Hydrochloride EP Impurity A
Stability Hygroscopic
Applications 4-Epi Minocycline (Minocycline EP Impurity A) is an impurity of Minocycline.
References Naidong, W., et al.: J. Pharm. Biomed. Anal., 13, 905 (1995)

Formula: C₂₃H₂₇N₃O₇

Color and Shape: Neat

Molecular weight: 457.48

Ref: TR-E588540

4-Epiminocycline

CAS: 43168-51-0

4-Epiminocycline is a pharmaceutical preparation that belongs to the class of antibiotics. It is a drug substance that is used in the manufacture of other drugs and as an individual drug for the treatment of various skin conditions and for the prevention of malaria. 4-Epiminocycline has been shown to be effective against bacteria by binding to DNA, preventing transcription and replication. The drug binds to plasma proteins and erythrocytes with high affinity, but it does not bind well to intestinal cells or lung tissue. 4-Epiminocycline has been shown to be effective against Mycobacterium tuberculosis, Mycobacterium avium complex, Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. This antibiotic also prevents the formation of biofilms by these bacteria.

Formula: C₂₃H₂₇N₃O₇

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 457.48 g/mol

Ref: 3D-FE159617

4-epi Minocycline

CAS: 43168-51-0

4-epiMinocycline, recognized as a primary degradation product and a probable impurity in minocycline commercial formulations, is derived from minocycline, a broad-spectrum tetracycline antibiotic notable for its extended serum half-life. Besides treating acne, especially in older patients, minocylvania exhibits significant anti-inflammatory and neuroprotective effects.

Formula: C₂₃H₂₇N₃O₇

Color and Shape: Solid

Molecular weight: 457.483

Ref: TM-T85208