CAS 43169-50-2
:D-Streptamine, O-6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:?)
Description:
D-Streptamine, O-6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:?) is a complex glycoside with notable structural features that contribute to its biological activity. This compound is characterized by a streptamine core, which is a derivative of aminoglycoside antibiotics, and is modified with various sugar moieties, including a glucopyranosyl and an arabinopyranosyl unit. The presence of amino and methylamino groups enhances its solubility and interaction with biological targets. The sulfate group indicates that it may have enhanced stability and solubility in physiological conditions. This compound is of interest in medicinal chemistry due to its potential antimicrobial properties, particularly against certain bacterial strains. Its intricate structure suggests that it may interact with ribosomal RNA, inhibiting protein synthesis, a common mechanism of action for aminoglycosides. Overall, D-streptamine's unique structural characteristics position it as a significant compound in the study of antibiotic development and glycoside chemistry.
Formula:C19H38N4O10·xH2O4S
InChI:InChI=1S/C19H38N4O10.H2O4S/c1-19(29)5-30-17(13(28)16(19)23-2)32-14-6(21)3-7(22)15(12(14)27)33-18-11(26)10(25)9(24)8(4-20)31-18;1-5(2,3)4/h6-18,23-29H,3-5,20-22H2,1-2H3;(H2,1,2,3,4)/t6-,7+,8-,9-,10+,11-,12-,13-,14+,15-,16-,17-,18-,19+;/m1./s1
InChI key:InChIKey=DSKCFEUMUAHNEE-NYKBMUPHSA-N
SMILES:O([C@H]1[C@H](O)[C@@H](O[C@@H]2[C@H](O)[C@@H](NC)[C@@](C)(O)CO2)[C@H](N)C[C@@H]1N)[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O.S(=O)(=O)(O)O
Synonyms:- (1R,2R,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 6-amino-6-deoxy-alpha-D-glucopyranoside sulfate (salt)
- (2R,3S,4S,5R,6R)-2-(Aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}tetrahydro-2H-pyran-3,4,
- (2R,3S,4S,5R,6R)-2-(Aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}tetrahydro-2H-pyran-3,4,5-triolsulfat(salt)
- (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}tetrahydro-2H-pyran-3,4,5-triol sulfate (salt)
- 43169-50-2
- 5-Triolsulfat(Salt)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-6-amino-6-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:?)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-6-amino-6-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (salt)
- Betamicin sulfate
- Gentamicin B sulfate
- Gentamycin B sulfate
- NSC 180972
- D-Streptamine, O-6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:?)
- (1R,2R,3S,4R,6S)-4,6-Diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 6-amino-6-deoxy-alpha-D-glucopyranoside sulfate (1:1)
- See more synonyms
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Found 3 products.
Gentamicin B Sulfate
CAS:Controlled ProductFormula:C19H38N4O10·H2O4SColor and Shape:NeatMolecular weight:580.604Gentamicin B sulfate
CAS:<p>Gentamicin B sulfate is an aminoglycoside antibiotic, which is produced through the fermentation process involving the actinomycete Micromonospora purpurea. This antibiotic functions primarily by binding to the 30S ribosomal subunit of bacteria, thereby inhibiting protein synthesis. This action disrupts the initiation of protein chain formation, ultimately leading to bacterial cell death. Gentamicin B sulfate is particularly effective against a variety of Gram-negative bacteria and some Gram-positive strains.</p>Formula:C19H40N4O14SPurity:Min. 95%Molecular weight:580.60 g/mol


