CAS 4317-14-0

Amitriptylinoxide

Description:

Amitriptylinoxide is a chemical compound that is a derivative of amitriptyline, a tricyclic antidepressant. It is characterized by its structural modification, which includes the presence of an oxide group. This modification can influence its pharmacological properties compared to its parent compound. Amitriptylinoxide is primarily known for its potential use in the treatment of depression and other mood disorders, similar to other tricyclic antidepressants. The compound exhibits a range of pharmacological activities, including serotonin and norepinephrine reuptake inhibition, which contributes to its antidepressant effects. Additionally, it may have sedative properties, making it useful in managing anxiety and sleep disturbances. The compound's safety profile, side effects, and interactions with other medications are important considerations in clinical use. As with many pharmaceuticals, the specific characteristics, including solubility, stability, and bioavailability, can vary and are critical for its therapeutic application. Overall, amitriptylinoxide represents an important compound in the field of psychopharmacology, with ongoing research into its efficacy and safety.

Formula: C₂₀H₂₃NO

InChI: InChI=1/C20H23NO/c1-21(2,22)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3

InChI key: InChIKey=ZPMKQFOGINQDAM-UHFFFAOYSA-N

SMILES: C(CCN(C)(C)=O)=C1C=2C(CCC=3C1=CC=CC3)=CC=CC2

Synonyms:

• 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-N-oxide
• 10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta(sup 5,gamma)-propylamine N-oxide
• 10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta5,gamma-propylamine-N-oxide
• 3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)-N,N-dimethylpropylamin N-oxid
• 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-N-oxide
• 5H-Dibenzo[a,d]cycloheptene-Δ^5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-, N-oxide
• Ambivalon
• Amioxid
• Amitriptilinoxido
• Amitriptilinoxido [INN-Spanish]
• Amitriptyline N-oxide
• Amitriptyline oxide
• Amitriptylinoxide [INN]
• Amitriptylinoxidum
• Amitriptylinoxidum [INN-Latin]
• Amitriptylinoxyde
• Amitriptylinoxyde [INN-French]
• Brn 2385442
• Equilibrin
• Unii-Tyr2U59Wma
• [3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl]dimethylamine oxide
• Amitriptylinoxide
• Amitriptylinoxide
• 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-, N-oxide
• Nortriptyline EP Impurity J (Amitriptyline N-Oxide)
• Nortriptyline Impurity 10 (Nortriptyline EP Impurity J)
• ZPMKQFOGINQDAM-UHFFFAOYSA-N
• Amitriptyline Impurity 8
• 1-?Propanamine, 3-?(10,?11-?dihydro-?5H-?dibenzo[a,?d]?cyclohepten-?5-?ylidene)?-?N,?N-?dimethyl-?, N-?oxide
• Amitriptyline N-Oxide (Nortriptyline EP Impurity J)
• Nortriptyline EP Impurity J

Nortriptyline EP Impurity J (Amitriptyline N-Oxide)

CAS: 4317-14-0

Formula: C₂₀H₂₃NO

Molecular weight: 293.41

Ref: 4Z-N-3619

Amitriptyline N-Oxide-d6

Controlled Product

CAS: 4317-14-0

Formula: C₂₀H₁₇D₆NO

Color and Shape: Neat

Molecular weight: 299.44

Ref: TR-A633357

Amitriptyline N-Oxide

CAS: 4317-14-0

Formula: C₂₀H₂₃NO

Color and Shape: Neat

Molecular weight: 293.40

Ref: TR-A633355

Amitriptyline N-Oxide-13C3

Controlled Product

CAS: 4317-14-0

Formula: C₃C₁₇H₂₃NO

Color and Shape: Neat

Molecular weight: 296.381

Ref: TR-A633358

Amitriptyline N-oxide

CAS: 4317-14-0

Amitriptyline N-oxide is an amine that is metabolized in the liver by cytochrome P450 and N-oxidases. It has been shown to inhibit the uptake of a number of drugs, including imatinib, and inhibit their oxidation by cytochrome p450. Amitriptyline N-oxide has also been shown to affect blood pressure in humans. The compound class of amitriptyline N-oxide includes a number of other drugs, such as octopamine, tyramine, dopamine, ephedrine and amphetamine. Amitriptyline N-oxide is oxidized to amitriptyline by human liver microsomes and can be used as a biochemical probe for compounds with similar structures. The profile of amitriptyline N-oxide can be used to identify other compounds with similar structures.

Formula: C₂₀H₂₃NO

Purity: Min. 95%

Molecular weight: 293.4 g/mol

Ref: 3D-FA178736

Amitriptyline N-Oxide

CAS: 4317-14-0

Formula: C₂₀H₂₃NO

Molecular weight: 293.40

Ref: ST-EA-CP-A39008

Amitriptylinoxide

CAS: 4317-14-0

Amitriptylinoxide is an antidepressant.

Formula: C₂₀H₂₃NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 293.4

Ref: TM-T25081