CAS 431898-65-6

N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide

Description:

N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide, with the CAS number 431898-65-6, is a chemical compound that belongs to the class of pyridinecarboxamides. This substance features a complex structure characterized by a pyridoindole core, which is fused with a pyridine ring and contains a chloro substituent. The presence of the carboxamide functional group contributes to its potential as a bioactive molecule, possibly influencing its solubility and interaction with biological targets. The compound may exhibit various pharmacological properties, making it of interest in medicinal chemistry and drug development. Its unique structural features suggest potential applications in areas such as cancer research or neuropharmacology, although specific biological activities would require empirical investigation. As with many synthetic compounds, safety and handling precautions should be observed, and its stability under various conditions should be assessed for practical applications.

Formula: C₁₇H₁₁ClN₄O

InChI: InChI=1S/C17H11ClN4O/c18-11-6-13-12-3-5-20-9-15(12)21-16(13)14(7-11)22-17(23)10-2-1-4-19-8-10/h1-9,21H,(H,22,23)

InChI key: InChIKey=JZRMBDHPALEPDM-UHFFFAOYSA-N

SMILES: N(C(=O)C=1C=CC=NC1)C2=C3C(C=4C(N3)=CN=CC4)=CC(Cl)=C2

Synonyms:

• 3-Pyridinecarboxamide, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-
• N-(6-Chloro-9H-beta-carbolin-8-yl)pyridine-3-carboxamide
• N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide
• Ps-1145

3-Pyridinecarboxamide, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-

CAS: 431898-65-6

Formula: C₁₇H₁₁ClN₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 322.7484

Ref: IN-DA006ZB1

N-(6-Chloro-9H-Pyrido[3,4-B]Indol-8-Yl)Nicotinamide

CAS: 431898-65-6

N-(6-Chloro-9H-Pyrido[3,4-B]Indol-8-Yl)Nicotinamide

Purity: 98%

Molecular weight: 322.75g/mol

Ref: 54-OR1023185

PS-1145

CAS: 431898-65-6

PS-1145

Purity: ≥95%

Molecular weight: 322.75g/mol

Ref: 54-BUP08077

PS-1145 dihydrochloride

CAS: 431898-65-6

Formula: C₁₇H₁₁ClN₄O·2HCl

Molecular weight: 395.67

Ref: 7W-GL0621

PS-1145

CAS: 431898-65-6

PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.

Formula: C₁₇H₁₁ClN₄O

Purity: 98.81% - >99.99%

Color and Shape: Solid

Molecular weight: 322.75

Ref: TM-T3094

PS-1145

CAS: 431898-65-6

PS-1145 is a chemical inhibitor that belongs to the class of small molecule inhibitors. PS-1145 binds to the IL2 receptor and blocks the activation of BCL-2 protein, leading to cell death by inhibiting the production of proteins vital for cell division. It also inhibits inhibitory proteins such as IκBα and NEMO, which are important for NF-κB signaling. PS-1145 induces oxidative injury and caspase-independent cell death in cells by binding to DNA at response elements, thereby inhibiting transcriptional activity.

Formula: C₁₇H₁₁ClN₄O

Purity: Min. 95%

Molecular weight: 322.75 g/mol

Ref: 3D-GSA89865