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CAS 432-33-7

:

(6α,11β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione

Description:
The chemical substance with the name "(6α,11β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione" and CAS number "432-33-7" is commonly known as fluocinolone acetonide. It is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in dermatology for the treatment of various skin conditions, including eczema, psoriasis, and dermatitis. The compound features a fluorine atom, which enhances its potency and stability, and an acetyloxy group that contributes to its pharmacological activity. Fluocinolone acetonide exhibits a high affinity for glucocorticoid receptors, leading to a reduction in inflammation and immune response. Its structure includes a steroid backbone, characterized by a four-ring core, with specific functional groups that dictate its biological activity. The compound is typically formulated in topical preparations, allowing for localized treatment with minimal systemic absorption. As with all corticosteroids, its use should be monitored to avoid potential side effects, including skin thinning and systemic effects with prolonged use.
Formula:C24H31FO6
InChI:InChI=1S/C24H31FO6/c1-13-9-18-16-6-8-23(30,20(29)12-31-14(2)26)22(16,4)11-19(28)24(18,25)21(3)7-5-15(27)10-17(13)21/h5,7,10,13,16,18-19,28,30H,6,8-9,11-12H2,1-4H3/t13-,16-,18-,19-,21-,22-,23-,24-/m0/s1
InChI key:InChIKey=KYVZRGYRHWSJFB-OOACPSMNSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(COC(C)=O)=O)(O)CC3)[H])(C[C@H](C)C=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-6α-methyl-, 21-acetate
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-6-methyl-, (6α,11β)-
  • (6α,11β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
  • 9α-Fluoro-6α-methylprednisolone 21-acetate
  • 6α-Methyl-9α-fluoroprednisolone-21-acetate
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Found 2 products.
  • 9α-Fluoro-6α-methylprednisolone 21-Acetate
    TRC
    + Info

    9α-Fluoro-6α-methylprednisolone 21-Acetate

    Controlled Product
    CAS:
    <p>Applications 9α-Fluoro-6α-methylprednisolone 21-Acetate displays oral thymolytic activity in rats. In addition, as a prednisolone derivative, it maintains potential anti-inflammatory and anti-oxidant properties.<br>References Allen, W. et al.: J. Med. Pharm. Chem., 5. 133 (1962); Hall, E.D., et al.: J. Neurosurg., 76, 13 (1992), Hommes, O.R., et al.: Mult. Scler., 1, 327 (1996), Bracken, M.B., et al.: J. Neurosurg., 89, 699 (1998), Dammers, J.W.H.H., et al.: Brit. Med. J., 319, 884 (1999)<br></p>
    Formula:C24H31FO6
    Color and Shape:Neat
    Molecular weight:434.498

    Ref: TR-F597810

    100mg
    3,477.00€
  • 9α-Fluoro-6α-methylprednisolone 21-acetate
    Biosynth
    + Info

    9α-Fluoro-6α-methylprednisolone 21-acetate

    Controlled Product
    CAS:
    <p>9α-Fluoro-6α-methylprednisolone 21-acetate is an analog of the hormone cortisol and has potent anti-inflammatory and immunosuppressive properties. It is also being studied for its potential anticancer activity. This compound inhibits cyclin-dependent kinases, which are involved in regulating cell division and growth. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in animal models. Additionally, it has been found in human urine, indicating that it may have potential as a biomarker for cancer diagnosis or monitoring.</p>
    Formula:C24H31FO6
    Purity:Min. 95%
    Molecular weight:434.5 g/mol

    Ref: 3D-AAA43233

    25mg
    774.00€
    50mg
    1,167.00€
    100mg
    1,625.00€