CAS 433289-84-0

(βR,δR)-β,δ-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid

Description:

The chemical substance known as "(βR,δR)-β,δ-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid" with the CAS number 433289-84-0 is a complex organic compound characterized by its unique structural features. It contains a pyrrole ring, which is a five-membered aromatic heterocycle, and is substituted with multiple functional groups, including hydroxyl (-OH) groups and a phenylamino carbonyl moiety. The presence of the isopropyl group (1-methylethyl) contributes to its hydrophobic characteristics, while the diphenyl and phenylamino groups enhance its potential for interactions with biological targets. This compound may exhibit interesting pharmacological properties due to its structural complexity and the presence of stereocenters, indicated by the (βR,δR) configuration. Its solubility, stability, and reactivity can be influenced by the functional groups and the overall molecular architecture, making it a candidate for further investigation in medicinal chemistry and drug development.

Formula: C₃₃H₃₆N₂O₅

InChI: InChI=1S/C33H36N2O5/c1-22(2)31-30(33(40)34-25-16-10-5-11-17-25)29(23-12-6-3-7-13-23)32(24-14-8-4-9-15-24)35(31)19-18-26(36)20-27(37)21-28(38)39/h3-17,22,26-27,36-37H,18-21H2,1-2H3,(H,34,40)(H,38,39)/t26-,27-/m1/s1

InChI key: InChIKey=SWFBJYRYCRZMSB-KAYWLYCHSA-N

SMILES: C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@H](C[C@H](CC(O)=O)O)O)C2C(C)C)C3=CC=CC=C3)C4=CC=CC=C4

Synonyms:

• (bR,dR)-b,d-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid
• 1H-Pyrrole-1-heptanoic acid, β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-, (βR,δR)-
• Defluoro Atorvastatin
• Defluoro atorvastatin calcium salt
• Atorvastatin EP IMP A
• Atorvastatin Calcium Hydrate Impurity A
• Atorvastatin EP Impurity A Calcium Salt (Defluoro Atorvastatin Calcium Salt)
• 1H-Pyrrole-1-heptanoicacid, b,d-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-,(bR,dR)-
• Desfluoro atorvastatin
• (3R,5R)-7-[2,3-diphenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
• (betaR,deltaR)-beta,delta-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid

Arbutin-13C6

CAS: 433289-83-9, 433289-84-0

Formula: C₁₂H₁₆O₇

Molecular weight: 278.19

Ref: 4Z-A-132004

Desfluoroatorvastatin

CAS: 433289-84-0

Formula: C₃₃H₃₆N₂O₅

Color and Shape: Neat

Molecular weight: 540.65

Ref: TR-D791750

Atorvastatin EP Impurity A

CAS: 433289-84-0

Formula: C₃₃H₃₆N₂O₅

Molecular weight: 540.66

Ref: ST-EA-CP-A32001

Desfluoro atorvastatin

CAS: 433289-84-0

Desfluoro atorvastatin is a crystalline polymorph of atorvastatin that has been shown to have improved flowrate and dissolution profile compared with the conventional form. Desfluoro atorvastatin is synthesized by adding a fluorine atom to a specific position in the molecule. The synthesis procedure includes chromatographic purification and analysis of impurities, which are then eliminated by diode laser irradiation. Impurities may also be eliminated through hydrogenation or recrystallization.

Formula: C₃₃H₃₆N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 540.65 g/mol

Ref: 3D-ID71941

Defluoro Atorvastatin Sodium Salt

Controlled Product

CAS: 433289-84-0

Applications An Atorvastatin impurity in bulk drug and tablets.

Formula: C₃₃H₃₅N₂NaO₅

Color and Shape: Neat

Molecular weight: 562.631

Ref: TR-D229010

Desfluoro-atorvastatin

CAS: 433289-84-0

Desfluoro-atorvastatin is an impurity of atorvastatin, an oral HMG-CoA reductase inhibitor that lowers blood lipids.

Formula: C₃₃H₃₆N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 540.65

Ref: TM-T15099