CAS 4336-46-3

N-[(diaminomethylidene)carbamoyl]pentofuranosylamine - 2,4,6-trinitrophenol (1:1)

Description:

N-[(Diaminomethylidene)carbamoyl]pentofuranosylamine - 2,4,6-trinitrophenol (1:1), with CAS number 4336-46-3, is a chemical compound that exhibits unique structural and functional characteristics. This substance features a pentofuranosylamine moiety, which is a sugar derivative, linked to a trinitrophenol group, known for its explosive properties. The presence of the diaminomethylidene and carbamoyl groups suggests potential reactivity and biological activity, possibly influencing its solubility and interaction with biological systems. The compound's dual nature, combining a carbohydrate structure with a highly nitrated aromatic compound, may impart interesting properties, such as potential use in pharmaceuticals or as a biochemical probe. However, due to the presence of the trinitrophenol component, it may also pose safety concerns related to stability and handling, necessitating careful consideration in laboratory settings. Overall, this compound represents a fascinating intersection of organic chemistry and potential applications in various fields, including medicinal chemistry and materials science.

Formula: C₁₃H₁₇N₇O₁₂

InChI: InChI=1/C7H14N4O5.C6H3N3O7/c8-6(9)11-7(15)10-5-4(14)3(13)2(1-12)16-5;10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h2-5,12-14H,1H2,(H5,8,9,10,11,15);1-2,10H

SMILES: C(C1C(C(C(N=C(NC(=N)N)O)O1)O)O)O.c1c(cc(c(c1N(=O)=O)O)N(=O)=O)N(=O)=O

Azacitidine Related Compound C (1-β-D-Ribofuranosyl-3-guanylurea picrate)

CAS: 4336-46-3

Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose; sugar ethers and sugar esters, and their salts, nesoi

Formula: C₇H₁₄N₄O₅·C₆H₃N₃O₇

Color and Shape: Yellow Powder

Molecular weight: 234.09642

Ref: 45-1045574

1-(Diaminomethylene)-3-(β-D-ribofuranosyl)urea Picrate

CAS: 4336-46-3

Formula: C₁₃H₁₇N₇O₁₂

Purity: 80%

Color and Shape: Solid

Molecular weight: 463.3138

Ref: IN-DA003D30

Azacitidine USP Related Compound C

CAS: 4336-46-3

Formula: C₇H₁₄N₄O₅C₆H₃N₃O₇

Molecular weight: 234.2 : 229.1

Ref: ST-EA-CP-A35003

1-(Diaminomethylene)-3-b-D-ribofuranosyl-urea Picrate

Controlled Product

CAS: 4336-46-3

Impurity Azacitidine USP Related Compound C
Stability Hygroscopic
Applications 1-(Diaminomethylene)-3-β-D-ribofuranosyl-urea Picrate is a related compound of Azacitidine, a DNA metnyltransferase (DNMT) inhibitor for treating myelodysplastic syndromes (MDS).
References Rajendiran, C., et al.: PCT Int. Appl. WO 2012135405 A1 20121004 (2012); Ziemba, A., et al.: Chemother Res Pract 965826, 9 (2011); Beisler, J. A., et al.: J. Carbohyd. Chem 4, 281 (1977)

Formula: C₇H₁₄N₄O₅·C₆H₃N₃O₇

Color and Shape: Yellow

Molecular weight: 463.31

Ref: TR-D417660

1-β-D-Ribofuranosyl-3-guanylurea picrate

Controlled Product

CAS: 4336-46-3

1-beta-D-Ribofuranosyl-3-guanylurea picrate is also known as 1-(diaminomethylene)-3-(beta-D-ribofuranosyl)urea picrate, 1-amidino-3-b-D-ribofuranosylurea monopicrate and Azacitidine Related Compound C. 1-beta-D-Ribofuranosyl-3-guanylurea picrate is an impurity generated from the hydrolysis of the drug Azacitidine, available on the market with the trade name Vidaza. Azacitidine is a chemical analogue of cytidine and is used in the treatment of myelodysplastic syndrome.

Formula: C₇H₁₄N₄O₅•C₆H₃N₃O₇

Purity: Min. 95.0 Area-%

Color and Shape: Powder

Molecular weight: 463.31 g/mol

Ref: 3D-OR63453