CAS 434-13-9
:Lithocholic acid
Description:
Lithocholic acid is a bile acid that plays a crucial role in the digestion and absorption of fats and fat-soluble vitamins in the intestine. It is a steroid acid, characterized by a four-ring structure typical of steroids, with a hydroxyl group at the C-3 position and a side chain that contributes to its amphipathic nature, allowing it to interact with both lipids and water. Lithocholic acid is derived from the metabolism of cholesterol and is primarily produced in the liver. It is known for its role in emulsifying fats, facilitating their breakdown by digestive enzymes. Additionally, lithocholic acid has been studied for its potential effects on various physiological processes, including its influence on gut microbiota and its implications in certain diseases, such as colorectal cancer. However, excessive levels of lithocholic acid can be toxic and may lead to liver damage or other health issues. Its CAS number, 434-13-9, is used for identification in chemical databases and regulatory contexts.
Formula:C24H40O3
InChI:InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
InChI key:InChIKey=SMEROWZSTRWXGI-HVATVPOCSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
Synonyms:- (3α,5β)-3-Hydroxycholan-24-oic acid
- 17β-(1-Methyl-3-carboxypropyl)etiocholan-3α-ol
- 3-Hydroxycholan-24-oic acid
- 3α-Hydroxy-5β-cholan-24-oate
- 3α-Hydroxy-5β-cholan-24-oic acid
- 3α-Hydroxy-5β-cholanic acid
- 3α-Hydroxy-5β-cholanoic acid
- 3α-Hydroxycholanic acid
- 5β-Cholan-24-oic acid, 3α-hydroxy-
- 5β-Cholanic acid, 3α-hydroxy-
- Acide lithocholique
- Acido Litocolico
- Lithocholic Acid
- Lithocholsaure
- Nsc 683770
- See more synonyms
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Found 14 products.
LITHOCHOLIC ACID CRS
CAS:LITHOCHOLIC ACID CRSFormula:C24H40O3Color and Shape:PowderMolecular weight:376.5726Lithocholic Acid MaxSpec® Standard
CAS:Formula:C24H40O3Purity:98%Color and Shape:SolidMolecular weight:376.5726Lithocholic Acid (Chenodeoxycholic Acid EP Impurity C, Ursodeoxycholic Acid EP Impurity C)
CAS:Formula:C24H40O3Color and Shape:White To Off-White SolidMolecular weight:376.58Lithocholic acid
CAS:Formula:C24H40O3Purity:≥ 98.0% (dried basis)Color and Shape:White to off-white powderMolecular weight:376.57Lithocholic Acid
CAS:Formula:C24H40O3Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalineMolecular weight:376.58Lithocholic acid
CAS:Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Formula:C24H40O3Purity:98% - 99.93%Color and Shape:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Molecular weight:376.57Lithocolic acid
CAS:Purity:98.0%Color and Shape:Solid, White to very pale yellow powderMolecular weight:376.58099365234375Lithocholic Acid
CAS:Controlled Product<p>Applications A cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.<br>References Brindle, J., et al.: Nat. Med., 12, 1439 (2002), Lindon, J., et al.: Biomarkers, 9, 1 (2004), Holmes, E., et al.: Cell, 134, 714 (2008),<br></p>Formula:C24H40O3Color and Shape:White To Off-WhiteMolecular weight:376.57Lithocholic acid
CAS:Controlled Product<p>Bile acid derivative; fat solubilizer</p>Formula:C24H40O3Color and Shape:White Off-White PowderMolecular weight:376.57 g/molLithocholic Acid (LCA) pure, 98%
CAS:Formula:C24H40O3Purity:min.98.0%Color and Shape:White to off -white, Crystalline powder, Clear, Colourless to pale yellowMolecular weight:376.57
