CAS 434-45-7

2,2,2-Trifluoro-1-phenylethanone

Description:

2,2,2-Trifluoro-1-phenylethanone, with the CAS number 434-45-7, is an organic compound characterized by its unique trifluoromethyl group and a phenyl ring attached to a carbonyl functional group. This compound typically appears as a colorless to pale yellow liquid and is known for its strong odor. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic characteristics. The presence of trifluoromethyl groups imparts notable chemical stability and influences its reactivity, making it useful in various synthetic applications, particularly in the pharmaceutical and agrochemical industries. Additionally, 2,2,2-Trifluoro-1-phenylethanone can participate in various chemical reactions, including nucleophilic additions and acylation processes. Safety considerations are important when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate precautions should be taken to minimize exposure. Overall, its distinctive structure and properties make it a valuable compound in organic synthesis and research.

Formula: C₈H₅F₃O

InChI: InChI=1S/C8H5F3O/c9-8(10,11)7(12)6-4-2-1-3-5-6/h1-5H

InChI key: InChIKey=KZJRKRQSDZGHEC-UHFFFAOYSA-N

SMILES: C(C(F)(F)F)(=O)C1=CC=CC=C1

Synonyms:

• (Trifluoroacetyl)benzene
• 1-Phenyl-2,2,2-trifluoro-ethanone
• 1-Phenyl-α,α,α-trifluoroethanone
• 2,2,2-Trifluoro-1-phenyl-1-ethanone
• 2,2,2-Trifluoro-1-phenylethanone
• 2,2,2-Trifluoroacetophenone
• Acetophenone, 2,2,2-trifluoro-
• Ethanone, 2,2,2-trifluoro-1-phenyl-
• NSC 42752
• Phenyl trifluoromethyl ketone
• Trifluoroacetophenone
• Trifluoromethyl phenyl ketone
• α,α,α-Trifluoroacetophenone
• ω,ω,ω-Trifluoroacetophenone

2,2,2-Trifluoroacetophenone, 98%

CAS: 434-45-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₅F₃O

Purity: 98%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 174.12

Ref: 02-A11403

2,2,2-Trifluoro-1-Phenylethanone

CAS: 434-45-7

Formula: C₈H₅F₃O

Purity: 98%

Color and Shape: Liquid

Molecular weight: 174.1199

Ref: IN-DA0032W5

2,2,2-Trifluoroacetophenone

CAS: 434-45-7

2,2,2-Trifluoroacetophenone

Formula: C₈H₅F₃O

Purity: 98%

Color and Shape: clear. colourless liquid

Molecular weight: 174.1199g/mol

Ref: 54-PC7200

2,2,2-Trifluoroacetophenone

CAS: 434-45-7

Formula: C₈H₅F₃O

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 174.12

Ref: 3B-T0848

2,2,2-Trifluoroacetophenone

CAS: 434-45-7

Formula: C₈H₅F₃O

Purity: 98%

Color and Shape: Liquid, Clear

Molecular weight: 174.122

Ref: 10-F001244

2,2,2-Trifluoroacetophenone

Controlled Product

CAS: 434-45-7

Applications 2,2,2-Trifluoroacetophenone is a fluorinated acetophenone with inhibitory activity of acetylcholinesterase. 2,2,2-Trifluoroacetophenone was shown to have neuroprotective activity by inhibiting apoptosis in cerebellar granule neurons.
References Brodbeck, U. et al.: Biochim. Biphys. Acta Enzymol., 567, 357 (1979); Kawase, M. et al.: Biol. Pharmac. Bull., 24, 1335 (2001);

Formula: C₈H₅F₃O

Color and Shape: Neat

Molecular weight: 174.12

Ref: TR-T786450