CAS 4342-03-4
:Dacarbazine
Description:
Dacarbazine, with the CAS number 4342-03-4, is an antineoplastic agent primarily used in chemotherapy for the treatment of various cancers, including melanoma and Hodgkin's lymphoma. It is classified as an alkylating agent, which means it works by interfering with the DNA replication process in cancer cells, ultimately leading to cell death. Dacarbazine is a white to off-white crystalline powder that is soluble in water and has a relatively low molecular weight. Its chemical formula is C6H10N4O2S, and it is often administered intravenously. The drug is known to have a range of side effects, including nausea, vomiting, and myelosuppression, which necessitates careful monitoring during treatment. Dacarbazine is typically used in combination with other chemotherapeutic agents to enhance its efficacy and improve patient outcomes. As with all chemotherapeutic agents, its use should be guided by a healthcare professional, considering the specific cancer type and patient health status.
Formula:C6H10N6O
InChI:InChI=1/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+
InChI key:InChIKey=FDKXTQMXEQVLRF-UHFFFAOYSA-N
SMILES:N(=NN(C)C)C1=C(C(N)=O)N=CN1
Synonyms:- (4E)-4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
- (Dimethyltriazeno)imidazolecarboxamide
- 1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazen-1-yl)-
- 1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-
- 1H-Imidazole-4-carboxamide, 5-[2-(dimethylamino)diazenyl]-
- 4(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide
- 4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
- 4-(Dimethyltriazeno)imidazole-5-carboxamide
- 5(4)-(3,3-Dimethyl-1-triazeno)imidazole-4(5)-carboxamide
- 5(or 4)-(3,3-Dimethyl-1-triazeno)imidazole-4(or 5)carboxamide
- 5-(3,3'-Dimethyl-1-triazeno)imidazole-4-carboxamide
- 5-(3,3-Dimethyl-1-triazen-1-yl)-1H-imidazole-4-carboxamide
- 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide
- 5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide
- 5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide
- 5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
- 5-(Dimethyltriazeno)imidazole-4-carboxamide
- 5-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide
- Biocarbazine R
- DIC
- DTIC-Dome
- Dacarbasine
- Dacarbazin
- Dacarbazino
- Deticene
- Detimedac
- Dtic
- Dtie
- Icdmt
- Icdt
- Imidazole-4(or 5)-carboxamide, 5(or 4)-(3,3-dimethyl-1-triazeno)-
- Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-
- Nci C04717
- Nsc 45388
- TOSLAB 25071
- 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamid
- DACARBAZINE
- 4-(3,3-dimethyltriazeno)imidazole-5-carboxamide
- biocarbaziner
- 5-(3,3-dimethyl-1-triazeno1-imidazole-4-carboxamid
- 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide
- 5-(3,3-dimethyl-1-triazenyl)-1h-imidazole-4-carboxamid
- See more synonyms
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Found 16 products.
Dacarbazine
CAS:Formula:C6H10N6OPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:182.19Dacarbazine
CAS:<p>Used in treatment of malignant melanoma and sarcomas. Generates methyl adducts to purine bases in DNA This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesa</p>Formula:C6H10N6OMolecular weight:182.18Dacarbazine
CAS:DacarbazineFormula:C6H10N6OColor and Shape:Off-White. To. Light YellowMolecular weight:182.1832DACARBAZINE CRS
CAS:<p>DACARBAZINE CRS</p>Formula:C6H10N6OColor and Shape:Crystalline Powder. White. Yellow. Powder.Molecular weight:182.1832Dacarbazine
CAS:<p>Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi</p>Formula:C6H10N6OColor and Shape:Off-White White PowderMolecular weight:182.091615-[(1E)-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide
CAS:Formula:C6H10N6OPurity:98%Color and Shape:SolidMolecular weight:182.1832Dacarbazine
CAS:<p>Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.</p>Formula:C6H10N6OPurity:99.78% - 99.87%Color and Shape:Ivory Microcrystaline Substance Physical Description White To Ivory Microcrystals Or Off-White Crystalline Solid (Ntp 1992)Molecular weight:182.18Dacarbazine
CAS:Formula:C6H10N6OPurity:98.0 - 102.0 % (anhydrous substance)Color and Shape:White to off-white or pale yellow crystalline powderMolecular weight:182.18Dacarbazine
CAS:Controlled ProductFormula:C6H10N6OColor and Shape:Off-White To Light YellowMolecular weight:182.18Dacarbazine
CAS:<p>Dacarbazine is an antineoplastic agent that inhibits the division of cancer cells by acting as a prodrug to produce the active form, dacarbazine trioxide. It has been shown to be effective in vitro for the treatment of melanoma and other solid tumours. Dacarbazine has been used in combination with other chemotherapeutic agents, such as temozolomide, for the treatment of brain tumours and carcinoid syndrome. The drug is associated with acute toxicities, including myelosuppression, alopecia, nausea and vomiting. These side effects can be reduced using interferon-alfa-2b. Dacarbazine has also been shown to have mitochondrial membrane potential (MMP) stabilizing properties that are independent of its cytotoxic effects on tumour cells.</p>Formula:C6H10N6OPurity:Min. 95%Color and Shape:White PowderMolecular weight:182.18 g/mol4-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide
CAS:Purity:98%Color and Shape:SolidMolecular weight:182.1869965
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