CAS 434938-41-7

K 41498

Description:

K 41498, identified by its CAS number 434938-41-7, is a chemical compound that falls under the category of small molecules. While specific details about its characteristics may not be widely available, compounds like K 41498 are often studied for their potential applications in pharmaceuticals or biochemistry. Typically, such substances may exhibit properties such as solubility in various solvents, stability under certain conditions, and specific reactivity profiles that can be influenced by their functional groups. The molecular structure, which can be inferred from its CAS number, plays a crucial role in determining its physical and chemical properties, including melting point, boiling point, and spectral characteristics. Additionally, the compound's biological activity, if applicable, would be of interest in medicinal chemistry, potentially impacting its efficacy and safety in therapeutic contexts. For precise information, including safety data and detailed chemical behavior, consulting specialized databases or scientific literature is recommended.

Formula: C₁₆₂H₂₇₆N₄₈O₄₆

Synonyms:

• D-PHE-HIS-LEU-LEU-ARG-LYS-NLE-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THR-ILE-NH2
• K 41498
• M.W. 3630.07 C162H276N48O46

K 41498

CAS: 434938-41-7

Formula: C₁₆₂H₂₇₆N₄₈O₄₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 3632.2188

Ref: IN-DA00D9QX

K41498

CAS: 434938-41-7

Potent CRF2α/β antagonist; Ki: 0.66/0.62 nM, weak for CRF1 (425 nM). Blocks sauvagine in hCRF2 cells and urocortin hypotension in rats.

Formula: C₁₆₂H₂₇₆N₄₈O₄₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 3632.26

Ref: TM-TP2009

K-41498 TFA Salt

Controlled Product

CAS: 434938-41-7

Applications K-41498 is a highly selective CRF2 receptor antagonist and used to treat hypertension in rodents (1,2).
References (1) Lawrence, A. et al.: Br. J. Pharmacol., 136, 896 (2002) (2) Rühmann, A. et al.: Peptides., 23, 453 (2002)

Formula: C₁₆₂H₂₇₆N₄₈O₄₆·C₂HF₃O₂

Color and Shape: Neat

Molecular weight: 3746.24

Ref: TR-K003000

K 41498

CAS: 434938-41-7

K 41498 is a human peptide that has cyclase inhibitory activity. It has been shown to increase the affinity of Urocortin for its receptor and to have negative inotropic effects on the heart, causing it to contract less forcefully. K 41498 also causes neuronal death in rats and mice, which may be due to its ability to inhibit protein synthesis.

Formula: C₁₆₂H₂₇₆N₄₈O₄₆

Purity: Min. 95%

Molecular weight: 3,632.26 g/mol

Ref: 3D-JSA93841

K 41498 trifluoroacetate

CAS: 434938-41-7

Please enquire for more information about K 41498 trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₆₂H₂₇₆N₄₈O₄₆•C₂HF₃O₂

Purity: Min. 95%

Molecular weight: 3,746.24 g/mol

Ref: 3D-BK183364