CAS 4350-09-8

5-Hydroxy-L-tryptophan

Description:

5-Hydroxy-L-tryptophan (5-HTP) is a naturally occurring amino acid and a chemical precursor to serotonin, a neurotransmitter that plays a crucial role in mood regulation, sleep, and appetite. It is derived from the seeds of the African plant Griffonia simplicifolia and is often used as a dietary supplement for its potential benefits in improving mood and alleviating symptoms of depression and anxiety. The substance is characterized by its ability to cross the blood-brain barrier, where it is converted into serotonin. 5-HTP is typically available in capsule or tablet form and is known for its relatively low toxicity. However, it can cause side effects such as gastrointestinal discomfort, drowsiness, and, in rare cases, serotonin syndrome when taken in excessive amounts or combined with other serotonergic medications. As with any supplement, it is advisable to consult a healthcare professional before use, especially for individuals with pre-existing health conditions or those taking other medications.

Formula: C₁₁H₁₂N₂O₃

InChI: InChI=1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1

InChI key: InChIKey=LDCYZAJDBXYCGN-VIFPVBQESA-N

SMILES: C([C@@H](C(O)=O)N)C=1C=2C(NC1)=CC=C(O)C2

Synonyms:

• (2S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
• (2S)-2-Azaniumyl-3-(5-hydroxy-1H-indol-3-yl)propanoate
• (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
• (S)-5-Hydroxytryptophan
• 5-Hydroxy-<span class="text-smallcaps">L</span>-tryptophan
• 5-Hydroxy-L-tryptophan
• 5-Hydroxyl-<span class="text-smallcaps">L</span>-tryptophan
• 5-Hydroxyl-L-tryptophan
• 5-Hydroxytryptophan
• <span class="text-smallcaps">L</span>-5-HTP
• <span class="text-smallcaps">L</span>-5-Hydroxytryptophan
• <span class="text-smallcaps">L</span>-Tryptophan, 5-hydroxy-
• Cincofarm
• L-5-Htp
• L-5-hydroxytryptophan
• Levothym
• Levotinine
• Oxitriptan
• Oxitriptano
• Oxyfan
• Pretonine
• Quietim
• Serotonyl
• Telesol
• Tript-Oh
• Triptene
• Tryptophan (L), 5-Hydroxy-
• Tryptophan, 5-hydroxy-, <span class="text-smallcaps">L</span>-
• Tryptophan, 5-hydroxy-, L-

5-Hydroxy-L-tryptophan

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 220.23

Ref: 3B-H0531

L-5-Hydroxytryptophan hydrate, 98%

CAS: 4350-09-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₁₂N₂O₃

Purity: 98%

Color and Shape: Powder, White to cream

Molecular weight: 220.23

Ref: 02-A13954

5-Hydroxy-L-Tryptophan

CAS: 4350-09-8

5-Hydroxy-L-Tryptophan analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₁H₁₂N₂O₃

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 220.23

Ref: 11-5517S

5-Hydroxy-L-tryptophan

CAS: 4350-09-8

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₁₁H₁₂N₂O₃

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 220.08479

Ref: 45-1329913

(2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 220.2246

Ref: IN-DA00I8BR

L-5-Hydroxytryptophan

CAS: 4350-09-8

L-5-Hydroxytryptophan (L-5-HTP) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.

Formula: C₁₁H₁₂N₂O₃

Purity: 99.78% - 99.96%

Color and Shape: Less To Pale Pink Crystals (Ntp 1992) Physical Description Colorless To Pale Pink Crystals (Ntp 1992)

Molecular weight: 220.22

Ref: TM-T1379

Tryptophan EP Impurity D

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Color and Shape: Gray Solid

Molecular weight: 220.23

Ref: 4Z-T-202

5-Hydroxy-L-tryptophan, 99.5%

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Purity: ≥ 99.5%

Color and Shape: White to off-white or pale beige powder

Molecular weight: 220.23

Ref: 7W-GM3498

L-5-Hydroxytryptophan

CAS: 4350-09-8

L-5-Hydroxytryptophan

Purity: ≥98%

Molecular weight: 220.22g/mol

Ref: 54-BUP16570

5-Hydroxy-L-tryptophan

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Purity: ≥ 99.0%

Color and Shape: White to off-white or pale beige powder

Molecular weight: 220.23

Ref: 7W-GM9337

5-Hydroxy-L-tryptophan-4,6,7-d3

CAS: 314062-44-7, 4350-09-8

Purity: 99 atom % D

Color and Shape: Off White To Grey Solid

Molecular weight: 241.26

Ref: 3U-D7154

(S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic Acid (5-Hydroxytryptophan)

Controlled Product

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Color and Shape: Neat

Molecular weight: 220.22

Ref: 86-MM0172.03

5-Hydroxytryptophan

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Purity: 95%~99%

Molecular weight: 220.228

Ref: BP-SBP03558

L-5-Hydroxytryptophan

CAS: 4350-09-8

L-5-Hydroxytryptophan

Purity: 98%

Molecular weight: 220.22g/mol

Ref: 54-BIK9010

5-hydroxy l-tryptophan

CAS: 4350-09-8

Nitrogen heterocyclic compound

Formula: C₁₁H₁₂N₂O₃

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 220.23

Ref: 5G-80477

5-Hydroxy L-Tryptophan

Controlled Product

CAS: 4350-09-8

Impurity L-5-Hydroxytryptophan(Tryptophan EP Impurity D)
Applications 5-Hydroxy-L-Tryptophan (L-5-Hydroxytryptophan(Tryptophan EP Impurity D)) is a hydroxylated metabolite of L-Tryptophan (T947210).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gartside, S., et al.: Eur. J. Pharmacol., 179, 103 (1990); Gijsman, H., et al.: J. Clin. Psychopharmacol., 22, 183 (2002),; Schruers, K., et al.: Psychiatry Res., 113, 237 (2002);

Formula: C₁₁H₁₂N₂O₃

Color and Shape: Neat

Molecular weight: 220.22

Ref: TR-H975710

5-Hydroxy-L-tryptophan

CAS: 4350-09-8

5-hydroxy-L-tryptophan (5HTP) is a naturally occurring amino acid that is an intermediate in the synthesis of the neurotransmitter serotonin. 5HTP appears to be able to increase levels of serotonin in the brain and may be used to treat mood disorders, including depression and anxiety. In clinical trials, 5HTP was found to be as effective as some antidepressant drugs for treating depression. Studies have shown that 5HTP increases locomotor activity and dopamine concentrations. It also increases physiological functions such as temperature regulation, heart rate, blood pressure, and respiration rate. The mechanism by which 5HTP achieves these effects is not yet fully understood but may involve its ability to bind to specific receptors on cells in different regions of the brain.
5HTP has been shown to inhibit polymerase chain reactions (PCR) in vitro by binding to DNA gyrase and topoisomerase IV enzyme activities. It also inhibits fatty acid oxidation in vitro by binding

Formula: C₁₁H₁₂N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 220.22 g/mol

Ref: 3D-FH05809

5-Hydroxy-L-Tryptophan

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Purity: 95%

Color and Shape: Powder or Crystalline Powder

Molecular weight: 220.228

Ref: 10-F218377

L-5-Hydroxytryptophan

CAS: 4350-09-8

L-5-Hydroxytryptophan (L-5HTP) is a naturally occurring amino acid that is useful for a wide range of chemical syntheses. L-5HTP is used as a substrate in the synthesis of serotonin, which is an important neurotransmitter. It is also used as a building block in the synthesis of other complex compounds and pharmaceuticals such as oxytocin, melatonin, and lysergic acid diethylamide (LSD). L-5HTP has been shown to have anti-inflammatory properties.

Formula: C₁₁H₁₂N₂O₃

Purity: Min. 98.0 Area-%

Molecular weight: 220.23 g/mol

Ref: 3D-H-8300

5-Hydroxy-L-Tryptophan extrapure, 98%

CAS: 4350-09-8

Formula: C₁₁H₁₂N₂O₃

Purity: min. 99%

Color and Shape: White to off - white  to pale brown, Powder

Molecular weight: 220.23

Ref: SR-67941