CAS 4360-12-7
:Ajmaline
Description:
Ajmaline is a naturally occurring alkaloid primarily derived from the plant Rauvolfia serpentina, commonly known as Indian snakeroot. It is classified as a class IA antiarrhythmic agent, which means it is used to treat certain types of cardiac arrhythmias by stabilizing the cardiac membrane and prolonging the action potential duration. Ajmaline has a complex chemical structure, characterized by a tetracyclic framework that includes a nitrogen atom, contributing to its pharmacological properties. The substance exhibits a range of biological activities, including sedative and antihypertensive effects, and has been studied for its potential therapeutic applications beyond cardiology. Ajmaline is typically administered in a clinical setting, and its effects can vary based on dosage and individual patient factors. As with many pharmacologically active compounds, it is essential to monitor for potential side effects, including hypotension and bradycardia. Overall, ajmaline represents an important compound in both traditional medicine and modern pharmacotherapy.
Formula:C20H26N2O2
InChI:InChI=1S/C20H26N2O2/c1-3-10-11-8-14-17-20(12-6-4-5-7-13(12)21(17)2)9-15(16(11)18(20)23)22(14)19(10)24/h4-7,10-11,14-19,23-24H,3,8-9H2,1-2H3/t10-,11?,14-,15-,16?,17-,18+,19+,20?/m0/s1
InChI key:InChIKey=CJDRUOGAGYHKKD-IWMNNKGHSA-N
SMILES:O[C@H]1C23[C@]([C@]4(N5[C@@](C2)(C1C(C4)[C@H](CC)[C@H]5O)[H])[H])(N(C)C=6C3=CC=CC6)[H]
Synonyms:- (15alpha,17R,21alpha)-ajmalan-17,21-diol
- (16xi,17R,21alpha)-ajmalan-17,21-diol
- (17R,21-alpha)-Ajmalan-17,21-diol
- (17R,21alpha)-Ajmalan-17,21-diol
- (17R,21α)-Ajmalan-17,21-diol
- (3xi,16xi,17R,20xi,21alpha)-ajmalan-17,21-diol
- 5H-6,10:11,12a-Dimethanoindolo[3,2-b]quinolizine, ajmalan-17,21-diol deriv.
- Ai3-62668
- Ajmalan-17,21-diol
- Ajmalan-17,21-diol, (17R,21-alpha)- (9CI)
- Ajmalan-17,21-diol, (17R,21alpha)-, compound with methanol (1:1)
- Ajmalan-17,21-diol, (17R,21α)-
- Ajmalin
- Ajmalina
- Ajmaline [JAN]
- Aritmina
- Cardiorythmine
- Cartagine
- Gilurytmal
- Ignazin
- Merabitol
- Nsc 15627
- Nsc 628054
- Raugalline
- Rauwolfin
- Rauwolfine
- Rhytmaton
- Ritmos
- Rytmalin
- Siddiqui
- Tachmalin
- Tajmalin
- Takhmalin
- Takycor
- Unii-1Pon08459R
- Ajmaline
- See more synonyms
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Found 13 products.
Ajmaline
CAS:Formula:C20H26N2O2Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:326.44Ajmaline
CAS:Ajmaline analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C20H26N2O2Purity:(HPLC) ≥90%Color and Shape:PowderMolecular weight:326.44Ajmaline
CAS:Formula:C20H26N2O2Purity:≥ 98.0%Color and Shape:White to off-white solidMolecular weight:326.44Ajmaline
CAS:<p>Ajmaline, a class Ia anti-arrhythmic, diagnoses Brugada syndrome and treats tachycardia; inhibits cardiac Kv1.5/Kv4.3 channels.</p>Formula:C20H26N2O2Purity:99.67% - 99.87%Color and Shape:SolidMolecular weight:326.43Ajmaline
CAS:Controlled Product<p>Applications An antiarrhythmic agent isolated from Rauwolfia serpentina.<br>References Galarreta, B., et al.: Bioorg. Med. Chem., 16, 6689 (2008), Sun, L., et al.: Plant Mol. Biol., 67, 455 (2008), Ruiz-May, E., et al.: Mol. Biotechnol., 41, 278 (2009),<br></p>Formula:C20H26N2O2Color and Shape:WhiteMolecular weight:326.43Ajmaline
CAS:<p>anti-arrhythmic agent</p>Formula:C20H26N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:326.43 g/molAjmaline pure, 98%
CAS:Formula:C20H24N2O2Purity:min 98%Color and Shape:Off white to pale yellow, PowderMolecular weight:326.44
