CAS 4360-12-7: Ajmaline

Description: Ajmaline is a naturally occurring alkaloid primarily derived from the plant Rauvolfia serpentina, commonly known as Indian snakeroot. It is classified as a class IA antiarrhythmic agent, which means it is used to treat certain types of cardiac arrhythmias by stabilizing the cardiac membrane and prolonging the action potential duration. Ajmaline has a complex chemical structure, characterized by a tetracyclic framework that includes a nitrogen atom, contributing to its pharmacological properties. The substance exhibits a range of biological activities, including sedative and antihypertensive effects, and has been studied for its potential therapeutic applications beyond cardiology. Ajmaline is typically administered in a clinical setting, and its effects can vary based on dosage and individual patient factors. As with many pharmacologically active compounds, it is essential to monitor for potential side effects, including hypotension and bradycardia. Overall, ajmaline represents an important compound in both traditional medicine and modern pharmacotherapy.

Formula: C₂₀H₂₆N₂O₂

InChI: InChI=1S/C20H26N2O2/c1-3-10-11-8-14-17-20(12-6-4-5-7-13(12)21(17)2)9-15(16(11)18(20)23)22(14)19(10)24/h4-7,10-11,14-19,23-24H,3,8-9H2,1-2H3/t10-,11?,14-,15-,16?,17-,18+,19+,20?/m0/s1

InChI key: InChIKey=CJDRUOGAGYHKKD-IWMNNKGHSA-N

SMILES: OC1N2C3CC(C1CC)C4C(O)C5(C=6C=CC=CC6N(C)C35)CC24

Synonyms:

• (15alpha,17R,21alpha)-ajmalan-17,21-diol
• (16xi,17R,21alpha)-ajmalan-17,21-diol
• (17R,21-alpha)-Ajmalan-17,21-diol
• (17R,21alpha)-Ajmalan-17,21-diol
• (17R,21α)-Ajmalan-17,21-diol
• (3xi,16xi,17R,20xi,21alpha)-ajmalan-17,21-diol
• 5H-6,10:11,12a-Dimethanoindolo[3,2-b]quinolizine, ajmalan-17,21-diol deriv.
• Ai3-62668
• Ajmalan-17,21-diol
• Ajmalan-17,21-diol, (17R,21-alpha)- (9CI)
• Ajmalan-17,21-diol, (17R,21alpha)-, compound with methanol (1:1)
• Ajmalan-17,21-diol, (17R,21α)-
• Ajmalin
• Ajmalina
• Ajmaline [JAN]
• Aritmina
• Cardiorythmine
• Cartagine
• Gilurytmal
• Ignazin
• Merabitol
• Nsc 15627
• Nsc 628054
• Raugalline
• Rauwolfin
• Rauwolfine
• Rhytmaton
• Ritmos
• Rytmalin
• Siddiqui
• Tachmalin
• Tajmalin
• Takhmalin
• Takycor
• Unii-1Pon08459R
• Ajmaline
• (+)-Ajmaline

Ajmaline

CAS: 4360-12-7

• Formula: C₂₀H₂₆N₂O₂
• Purity: >97.0%(T)(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 326.44

Ajmaline

CAS: 4360-12-7

Ajmaline analytical standard provided with chromatographic purity, to be used as reference material for qualitative …

• Formula: C₂₀H₂₆N₂O₂
• Purity: (HPLC) ≥90%
• Color and Shape: Powder
• Molecular weight: 326.44

AJMALINE

CAS: 4360-12-7

• Formula: C₂₀H₂₆N₂O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 326.4326

Ajmaline

CAS: 4360-12-7

• Purity: 98.19%
• Molecular weight: 326.43g/mol

Ajmaline

CAS: 4360-12-7

• Formula: C₂₀H₂₆N₂O₂
• Purity: 95%~99%
• Molecular weight: 326.44

Ajmaline

CAS: 4360-12-7

• Formula: C₂₀H₂₆N₂O₂
• Color and Shape: Neat
• Molecular weight: 326.43

Ajmaline

CAS: 4360-12-7

• Formula: C₂₀H₂₆N₂O₂
• Purity: ≥ 98.0%
• Color and Shape: White to off-white solid
• Molecular weight: 326.44

Ajmaline

CAS: 4360-12-7

Ajmaline, a class Ia anti-arrhythmic, diagnoses Brugada syndrome and treats tachycardia; inhibits cardiac Kv1.5/Kv4.3 channels.

• Formula: C₂₀H₂₆N₂O₂
• Purity: 99.67% - 99.87%
• Color and Shape: Solid
• Molecular weight: 326.43

Ajmaline

CAS: 4360-12-7

• Purity: 95.0%
• Molecular weight: 326.44

Ajmaline

CAS: 4360-12-7

anti-arrhythmic agent

• Formula: C₂₀H₂₆N₂O₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 326.43 g/mol

Ajmaline pure, 98%

CAS: 4360-12-7

• Formula: C₂₀H₂₄N₂O₂
• Purity: min 98%
• Color and Shape: Off white to pale yellow, Powder
• Molecular weight: 326.44

Ajmaline

CAS: 4360-12-7

Applications An antiarrhythmic agent isolated from Rauwolfia serpentina. References Galarreta, B., et al.: Bioorg. Med. …

• Formula: C₂₀H₂₆N₂O₂
• Color and Shape: White
• Molecular weight: 326.43