CAS 4360-47-8

Cinnamonitrile

Description:

Cinnamonitrile, with the CAS number 4360-47-8, is an organic compound characterized by its nitrile functional group attached to a cinnamyl structure. It typically appears as a colorless to pale yellow liquid with a distinctive aromatic odor reminiscent of cinnamon, which is derived from its structural similarity to cinnamaldehyde. The compound is known for its potential applications in organic synthesis and as an intermediate in the production of various pharmaceuticals and agrochemicals. Cinnamonitrile exhibits moderate solubility in organic solvents, while its reactivity is influenced by the presence of the nitrile group, allowing it to participate in nucleophilic addition reactions. Additionally, it may possess antimicrobial properties, making it of interest in the field of natural product chemistry. As with many nitriles, it is important to handle cinnamonitrile with care due to potential toxicity and environmental concerns. Proper safety measures should be observed when working with this compound in laboratory settings.

Formula: C₉H₇N

InChI: InChI=1S/C9H7N/c10-8-4-7-9-5-2-1-3-6-9/h1-7H

InChI key: InChIKey=ZWKNLRXFUTWSOY-UHFFFAOYSA-N

SMILES: C(=CC#N)C1=CC=CC=C1

Synonyms:

• (2E)-3-phenylprop-2-enenitrile
• (2Z)-3-phenylprop-2-enenitrile
• 1-Cyano-2-phenylethene
• 1-Cyano-2-phenylethylene
• 2-Propenenitrile, 3-phenyl-
• 3-Phenyl-2-propenenitrile
• 3-Phenylacrylonitrile
• 3-Phenylpropenenitrile
• Cinnamonitrilecistrans
• Cinnamyl nitrile
• NSC 42118
• NSC 49137
• Styryl cyanide
• β-Cyanostyrene
• β-Phenylacrylonitrile

Cinnamonitrile

CAS: 4360-47-8

Formula: C₉H₇N

Purity: 97%

Color and Shape: Liquid

Molecular weight: 129.1586

Ref: IN-DA00D8RG

3-Phenylacrylonitrile

CAS: 4360-47-8

Applications 3-Phenylacrylonitrile can be used to study signalling pathway. It can also inhibit EGF receptor kinase activity.
References Talalay, P., et al.: Proc. Natl. Acad. Sci. USA 85, 8261 (1988); Yasih, P., et al.: Science 242, 933 (1988)

Formula: C₉H₇N

Color and Shape: Neat

Molecular weight: 129.158

Ref: TR-P334000

3-Phenylacrylonitrile

CAS: 4360-47-8

3-Phenylacrylonitrile is an enzyme inhibitor that binds to the active site of the diphenolase enzyme, thereby inhibiting its function. The nitrile group in 3-phenylacrylonitrile is responsible for binding to the enzyme and forming a hydrogen bond with a zirconium oxide group. Hydroxyl groups on the phenyl ring also contribute to this reaction by making polar bonds with water molecules. This reaction is reversible and can be reversed by adding hydrochloric acid or by heating it at high temperatures. This reversibility provides a way to determine when 3-phenylacrylonitrile has bound to the active site of diphenolase by measuring the amount of heat released during the reaction.

Formula: C₉H₇N

Purity: Min. 95%

Molecular weight: 129.16 g/mol

Ref: 3D-EAA36047