CAS 437-64-9

Genkwanin

Description:

Genkwanin, with the CAS number 437-64-9, is a flavonoid compound primarily found in various plants, particularly in the genus *Sophora*. It is characterized by its yellow crystalline appearance and is known for its potential biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties. Genkwanin exhibits a flavone structure, which is a type of flavonoid characterized by a benzopyrone backbone. This compound is soluble in organic solvents but has limited solubility in water. Genkwanin has garnered interest in pharmacological research due to its potential therapeutic effects, including its role in modulating various biochemical pathways. Additionally, it may contribute to the health benefits associated with the consumption of plant-based diets. Its safety profile and efficacy in humans are still subjects of ongoing research, highlighting the need for further studies to fully understand its biological implications and potential applications in medicine and nutrition.

Formula: C₁₆H₁₂O₅

InChI: InChI=1/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

InChI key: InChIKey=JPMYFOBNRRGFNO-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC(=C1)C3=CC=C(O)C=C3)=CC(OC)=CC2O

Synonyms:

• 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-
• 4′,5-Dihydroxy-7-methoxyflavone
• 5,4′-Dihydroxy-7-methoxyflavone
• 5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
• 7-Methylapigenin
• 7-O-Methylapigenin
• Apigenin 7-O-methyl ether
• Apigenin 7-methyl ether
• Flavone, 4′,5-dihydroxy-7-methoxy-
• Gengkwanin
• Genkwanin
• Puddumetin
• 4',5-DIHYDROXY-7-METHOXYFLAVONE
• 7-METHOXYAPIGENIN

4',5-Dihydroxy-7-methoxyflavone, 97%

CAS: 437-64-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₆H₁₂O₅

Purity: 97%

Color and Shape: Yellow, Crystals or powder or crystalline powder

Molecular weight: 284.27

Ref: 02-L14169

Genkwanin

CAS: 437-64-9

Formula: C₁₆H₁₂O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 284.2635

Ref: IN-DA00DEPK

Genkwanin

CAS: 437-64-9

Formula: C₁₆H₁₂O₅

Molecular weight: 284.27

Ref: 7W-GY0551

5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one

CAS: 437-64-9

5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one

Formula: C₁₆H₁₂O₅

Purity: 98%

Molecular weight: 284.26

Ref: 54-OR1023911

Genkwanin

CAS: 437-64-9

Genkwanin

Formula: C₁₆H₁₂O₅

Purity: ≥95%

Molecular weight: 284.26

Ref: 54-BUP13844

Genkwanin

CAS: 437-64-9

Genkwanin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₆H₁₂O₅

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 284.28

Ref: 11-1147

Genkwanin (Standard)

CAS: 437-64-9

Genkwanin (Standard) is a reference standard for research and analysis in studies involving Genkwanin. 1. Genkwanin (Apigenin 7-methyl ether) exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance protein (MDR)-mediated efflux mechanisms.

Formula: C₁₆H₁₂O₅

Molecular weight: 284.26

Ref: TM-TMSM-2961

Genkwanin

CAS: 437-64-9

Genkwanin has antitumor, and anti-inflammatory activities, it enhances host immunity, decreases the inflammatory cytokine levels, and regulates the miR-101/MKP-1/MAPK pathway.Genkwanin may have anti-skin ageing activity, it can up-regulate the transcriptional activation of human type vii collagen gene promoter, stimulating the formation of anchoring fibrils at the basement membrane zone in skin contributed to preventing skin ageing; it also induces a decrease of melanin synthesis by inhibiting tyrosinase activity, it could as skin whitening agent in cosmetic preparations.

Formula: C₁₆H₁₂O₅

Purity: 95%~99%

Molecular weight: 284.267

Ref: BP-BP0636

4',5-Dihydroxy-7-methoxyflavone

CAS: 437-64-9

5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one

Formula: C₁₆H₁₂O₅

Purity: 98%

Molecular weight: 284.26

Ref: IN-DG92605

Genkwanin

CAS: 437-64-9

Genkwanin, an anti-inflammatory, regulates miR-11/MKP-1/MAPK pathway; diffuses passively and via MDR efflux.

Formula: C₁₆H₁₂O₅

Purity: 98.01% - ≥95%

Color and Shape: Solid

Molecular weight: 284.26

Ref: TM-T6S0095

Genkwanin

CAS: 437-64-9

Oxygen-heterocyclic compound

Formula: C₁₆H₁₂O₅

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 284.27

Ref: 5G-83500

Genkwanin

CAS: 437-64-9

Applications An antitumor constituent from the leaves of Aquilaria sinensis.
References Wollenweber, E., et al.: Nat. Prod. Communications, 2, 997 (2007), Smejkal, K., et al.: J. Nat. Prod., 70, 1244 (2007), Asai, T., et al.: Phytochemistry, 69, 1234 (2008),

Formula: C₁₆H₁₂O₅

Color and Shape: Neat

Molecular weight: 284.26

Ref: TR-G360000

Genkwanin

CAS: 437-64-9

Genkwanin is a flavonoid compound, which is a type of natural phenolic compound, often found in various plant sources, such as herbs like Daphne genkwa. This compound originates from plants known for their medicinal properties and is derived through the extraction and isolation of specific phytochemical constituents.

Formula: C₁₆H₁₂O₅

Purity: Min. 98 Area-%

Color and Shape: Yellow Powder

Molecular weight: 284.26 g/mol

Ref: 3D-FG23656

Genkwanin

CAS: 437-64-9

Ref: BE-促RMT23670

Genkwanin

CAS: 437-64-9

Ref: BE-RMT23670

GENKWANIN

CAS: 437-64-9

Purity: ≥97%

Molecular weight: 284.2669983

Ref: 10-F795534