CAS 4372-67-2

8-azidoadenosine

Description:

8-Azidoadenosine is a modified nucleoside that features an azido group (-N3) at the 8-position of the adenine base. This compound is characterized by its ability to participate in click chemistry reactions, making it a valuable tool in bioconjugation and labeling studies. It retains the purine structure of adenine, allowing it to interact with nucleic acid components, but the azido group introduces unique reactivity that can be exploited in various biochemical applications. 8-Azidoadenosine is often used in research to study nucleic acid interactions, cellular uptake, and the mechanisms of action of nucleoside analogs. Its stability under physiological conditions is generally good, although it may be sensitive to light and certain chemical environments. Additionally, due to its azido functionality, it can be used in photochemical reactions and as a precursor for the synthesis of other bioactive compounds. Overall, 8-azidoadenosine serves as an important compound in the fields of molecular biology and medicinal chemistry.

Formula: C₁₀H₁₂N₈O₄

InChI: InChI=1/C10H12N8O4/c11-7-4-8(14-2-13-7)18(10(15-4)16-17-12)9-6(21)5(20)3(1-19)22-9/h2-3,5-6,9,19-21H,1H2,(H2,11,13,14)/t3-,5-,6-,9-/m1/s1

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2c3c(c(N)ncn3)nc2N=[N+]=[NH-])O1)O)O)O

Synonyms:

• Adenosine, 8-azido-
• 8-Azidoadenosine
• (2R,3R,4S,5R)-2-(6-amino-8-azido-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
• 8-azido-adenosin
• 8-AZIDO-D-ADENOSINE
• 8-N3-ADO
• (2R,3R,4S,5R)-2-(6-amino-8-azidopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• (2R,3R,4S,5R)-2-(6-amino-8-azido-purin-9-yl)-5-methylol-tetrahydrofuran-3,4-diol
• (2R,3R,4S,5R)-2-(6-azanyl-8-azido-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

8-Azidoadenosine

CAS: 4372-67-2

Ref: 7W-GN6218

8-Azidoadenosine

CAS: 4372-67-2

Nucleoside Derivatives - 8-Modified purine nucleoside; Azido-nucleoside

Formula: C₁₀H₁₂N₈O₄

Color and Shape: Solid

Molecular weight: 308.25

Ref: TM-TNU0286

8-Azidoadenosine

CAS: 4372-67-2

8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.

Formula: C₁₀H₁₂N₈O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 308.25 g/mol

Ref: 3D-NA06674

8-Azido Adenosine

Controlled Product

CAS: 4372-67-2

Formula: C₁₀H₁₂N₈O₄

Color and Shape: Neat

Molecular weight: 308.25

Ref: TR-A821980