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CAS 4377-58-6

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5-fluorothiophene-2-carboxylic acid

Description:
5-Fluorothiophene-2-carboxylic acid is an organic compound characterized by its thiophene ring structure, which is a five-membered aromatic ring containing sulfur. The presence of a fluorine atom at the 5-position and a carboxylic acid group at the 2-position contributes to its unique chemical properties. This compound is typically a white to off-white solid and is soluble in polar solvents, such as water and alcohols, due to the carboxylic acid functionality. It exhibits acidic behavior, capable of donating a proton from the carboxylic group, which can influence its reactivity in various chemical reactions. The fluorine substituent can enhance the compound's electrophilicity and may also affect its biological activity, making it of interest in medicinal chemistry and material science. Additionally, 5-fluorothiophene-2-carboxylic acid can participate in various synthetic transformations, including coupling reactions and functional group modifications, making it a valuable intermediate in organic synthesis.
Formula:C5H3FO2S
InChI:InChI=1/C5H3FO2S/c6-4-2-1-3(9-4)5(7)8/h1-2H,(H,7,8)
SMILES:c1cc(F)sc1C(=O)O
Synonyms:
  • 2-Thiophenecarboxylic Acid, 5-Fluoro-
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