CAS 438-59-5
:10,11-Didehydronortriptyline hydrochloride
Description:
10,11-Didehydronortriptyline hydrochloride is a chemical compound that belongs to the class of tricyclic antidepressants. It is a derivative of nortriptyline, which is known for its use in the treatment of depression and certain types of pain. The compound features a tricyclic structure, which is characterized by three interconnected rings, contributing to its pharmacological activity. As a hydrochloride salt, it is typically more soluble in water, facilitating its use in pharmaceutical formulations. The compound acts primarily by inhibiting the reuptake of neurotransmitters such as norepinephrine and serotonin, thereby enhancing mood and alleviating depressive symptoms. Its chemical properties include a specific molecular weight and a defined melting point, which are essential for its characterization and quality control in pharmaceutical applications. Safety and efficacy profiles are critical, and like other tricyclic antidepressants, it may have side effects, including sedation and anticholinergic effects. Proper handling and dosage are essential to minimize risks associated with its use.
Formula:C19H20ClN
InChI:InChI=1/C19H19N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-13,20H,6,14H2,1H3;1H
InChI key:InChIKey=UZMPCPFDZYTEJG-UHFFFAOYSA-N
SMILES:C(CCNC)=C1C=2C(C=CC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:- 1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-, hydrochloride (9CI)
- 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride
- 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride (1:1)
- 10,11-Didehydronortriptyline hydrochloride
- 10,11-thelda-Nortriptyline hydrochloride
- 3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine hydrochloride (1:1)
- 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, N-methyl-, hydrochloride
- 5H-Dibenzo[a,d]cycloheptene-Δ<sup>5,γ</sup>-propylamine, N-methyl-, hydrochloride
- N 7068 hydrochloride
- Norproheptatriene hydrochloride
- Ro 4-6011
- 3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)propyl(methyl)ammonium chloride
- 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, N-methyl-, hydrochloride
- Nortriptyline Impurity 2 (Nortriptyline EP Impurity B)
- Cyclobenzaprine USP RC B Q: What is the storage condition of
- 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine Hydrochloride
- Einecs 207-118-3
- Cyclobenzaprine USP RC B
- Desmethyl Cyclobenzaprine Hydrochloride
- 3-(5H-Dibenzo[a,d][7]annulen-5-ylid
- Cyclobenzaprine Related CoMpound B
- Cyclobenzaprine Impurity 2(Cyclobenzaprine USP RC B)
- Cyclobenzaprine USP Related Compound B as Hydrochloride
- N-desmethyl Cyclobenzaprine HCl (USP RC B)
- Nortriptyline EP Impurity B HCl
- Cyclobenzaprine impurity 2/Cyclobenzaprine USP Related Compound B/Desmethyl Cyclobenzaprine Hydrochloride/3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine hydrochloride
- NORTRIPTYLINE EP IMPURITY B
- Cyclobenzaprine USP RC B Q: What is the CAS Number of
- Nortriptyline EP Impurity B HCl (N-Desmethyl Cyclobenzaprine HCl)
- Nortriptyline Hydrochloride Impurity B as Hydrochloride
- N-Desmethyl Cyclobenzaprine
- 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N-methylpropan-1-amine
- N-Desmethyl Cyclobenzaprine Hydrochloride
- Nortriptyline Hydrochloride EP Impurity B as Hydrochloride
- Cyclobenzaprine USP Related Compound B
- Cyclobenzaprine DesMethyl HCl
- N-Desmethylcyclobenzaprine hydrochloride solution
- N-Desmethyl Cyclobenzaprine-d3
- Cyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine (1154525)
- Cyclobenzaprine Related Compound B (10 mg) (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride)
- Cyclobenzaprine USP RC B Q: What are the applications of
- Desmethylcyclobenzaprine hydrochloride salt
- Cyclobenzaprine USP RC BQ: What is
- Cyclobenzaprine Related Compound B as Hydrochloride
- See more synonyms
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Found 8 products.
N-Desmethylcyclobenzaprine Hydrochloride (Norcyclobenzaprine Hydrochloride) 1.0 mg/ml in Methanol (as free base)
CAS:Color and Shape:Single SolutionCyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride)
CAS:Aromatic monoamines and their derivatives, salts thereof, nesoiFormula:C19H19N·HClColor and Shape:White PowderMolecular weight:261.151751-Propanamine,3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-,hydrochloride (1:1)
CAS:Formula:C19H20ClNColor and Shape:SolidMolecular weight:297.8218Nortriptyline EP Impurity B HCl (Cyclobenzaprine USP Related Compound B, N-Desmethyl Cyclobenzaprine HCl)
CAS:Formula:C19H19N·HClMolecular weight:261.37 36.463-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine Hydrochloride (Norcyclobenzaprine Hydrochloride)
CAS:Controlled ProductFormula:C19H19N·ClHColor and Shape:NeatMolecular weight:297.82Desmethyl Cyclobenzaprine Hydrochloride
CAS:Impurity Cyclobenzaprine USP Related Compound B
Applications Desmethyl Cyclobenzaprine (Cyclobenzaprine USP Related Compound B) is a metabolite of Cyclobenzaprine.
References Wang, R.W., et al.: Drug Metab. Dispos., 24, 786 (1996),Formula:C19H19N·ClHColor and Shape:Off-WhiteMolecular weight:297.82Desmethyl cyclobenzaprine hydrochloride
CAS:Desmethyl cyclobenzaprine hydrochloride is a metabolite of cyclobenzaprine, a drug used for the treatment of muscle spasms. Desmethyl cyclobenzaprine hydrochloride has been shown to have an increased potency for the termination of nerve impulses. These results were determined by in vivo studies using an assay on rat sciatic nerve and a study on human adrenergic receptors. This metabolite also shows potentiation effects with other drugs such as clonidine and prazosin, which are used to treat hypertension and anxiety, respectively. However, clinical relevance is still unknown due to the lack of data on desmethyl cyclobenzaprine hydrochloride's uptake and enhancement in humans.
Formula:C19H20ClNPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:297.82 g/mol
![Cyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamin…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F45%2Fthumb%2F1154525.jpg&w=3840&q=75)
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