SMI 4a, with the CAS number 438190-29-5, is a small molecule that has garnered attention in the field of chemical biology, particularly for its role as a selective inhibitor of the protein-protein interaction between the transcription factor c-Myc and its partner Max. This compound is characterized by its ability to disrupt the c-Myc/Max dimerization, which is crucial for the regulation of genes involved in cell proliferation and survival. SMI 4a exhibits a relatively low molecular weight and possesses a specific chemical structure that facilitates its binding to the target protein. Its selectivity and efficacy make it a valuable tool for research into cancer biology, as c-Myc is often overexpressed in various malignancies. Additionally, SMI 4a's properties may provide insights into the development of novel therapeutic strategies aimed at targeting oncogenic pathways. As with many small molecules, further studies are necessary to fully understand its pharmacokinetics, potential off-target effects, and overall biological impact.

SMI 4a

438190-29-5: SMI 4a, with the CAS number 438190-29-5, is a small molecule that has garnered attention in the field of chemical biology, particularly for its role as a selective inhibitor of the protein-protein interaction between the transcription factor c-Myc and its partner Max. This compound is characterized by its ability to disrupt the c-Myc/Max dimerization, which is crucial for the regulation of genes involved in cell proliferation and survival. SMI 4a exhibits a relatively low molecular weight and possesses a specific chemical structure that facilitates its binding to the target protein. Its selectivity and efficacy make it a valuable tool for research into cancer biology, as c-Myc is often overexpressed in various malignancies. Additionally, SMI 4a's properties may provide insights into the development of novel therapeutic strategies aimed at targeting oncogenic pathways. As with many small molecules, further studies are necessary to fully understand its pharmacokinetics, potential off-target effects, and overall biological impact.

SMI-4a

(Z)-SMI-4a

(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.

CAS 438190-29-5

SMI 4a

SMI-4a

Ref: IN-DA00733S

(Z)-SMI-4a

Ref: 54-BUP13346

(Z)-SMI-4a

Ref: TM-T3058

(Z)-SMI-4a

Ref: TR-S566000