CAS 4390-16-3

Sodium barbiturate

Description:

Sodium barbiturate, with the CAS number 4390-16-3, is a sodium salt of barbituric acid, classified as a barbiturate. It appears as a white to off-white crystalline powder and is soluble in water, which makes it useful in various applications, particularly in the medical field. Sodium barbiturate acts as a central nervous system depressant and has historically been used as a sedative and anesthetic. Its mechanism of action involves enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased inhibitory neurotransmission. This compound is also utilized in laboratory settings, particularly in the preparation of buffer solutions and as a reagent in biochemical assays. However, due to the potential for abuse and dependence, its clinical use has declined, and it is now more commonly replaced by safer alternatives. As with all barbiturates, caution is advised in its handling and administration due to the risk of overdose and significant side effects.

Formula: C₄H₃N₂NaO₃

InChI: InChI=1/C4H4N2O3.Na/c7-2-1-3(8)6-4(9)5-2;/h1H2,(H2,5,6,7,8,9);/q;+1

InChI key: InChIKey=HRYZPBSOAMTFEL-UHFFFAOYSA-N

SMILES: O=C1CC(=O)NC(=O)N1.[Na]

Synonyms:

• Barbituric acid, monosodium salt
• 2,4,6(1H,3H,5H)-Pyrimidinetrione, sodium salt (1:1)
• 2,4,6(1H,3H,5H)-Pyrimidinetrione, monosodium salt
• Sodium barbiturate
• Barbituric acid, sodium deriv.
• Monosodium barbiturate
• BARBITURIC ACID SODIUM SALT
• Einecs 224-507-3
• 2-Sodiooxy-4,6(1H,5H)-pyrimidinedione
• 2,4,6(1h,3h,5h)-pyrimidinetrione,monosodiumsalt
• Barbituric acid sodium
• Barbiturate sodium
• barbituricacid,monosodiumsalt
• 2,4,6(1H,2H,5H)-Pyrimidinetrione,monosodiumsalt
• Barbiturate sodiumQ: What is
• Barbiturate sodium Q: What is the CAS Number of
• SodiuM barbiturate >=97.0% (T)

Sodium barbiturate

Controlled Product

CAS: 4390-16-3

Sodium barbiturate is a drug that binds to the malonic acid cycle and inhibits the production of energy. It also has antimicrobial properties, inhibiting the growth of bacteria and fungi. Sodium barbiturate has been shown to have cytotoxic effects on colorectal adenocarcinoma cells in vitro, although it does not have any significant cytotoxicity against bowel disease cells (Caco2). This drug has been shown to be effective in treating inflammatory bowel disease in human subjects. The mechanism behind this effect is not yet fully understood but may involve its ability to react with metal ions as well as its ability to inhibit tubule cells by binding to their plasma membrane.

Formula: C₄H₂N₂Na₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 150.07 g/mol

Ref: 3D-EAA39016

SODIUM BARBITURATE

CAS: 4390-16-3

Formula: C₄H₃N₂NaO₃

Purity: 97%

Molecular weight: 150.068

Ref: IN-DA00D9QD