CAS 439146-24-4

Arachidonic Acid Glycidyl Ester

Controlled Product

CAS: 439146-24-4

Applications Arachidonic Acid Glycidyl Ester is an ester derivative of the essential fatty acid Arachidonic Acid (A765000) and an intermediate in the preparation of the endocannabinoid 2-Arachidonyl Glycerol (A765050). Arachidonic Acid Glycidyl Ester has inhibitory activity against monoacylglycerol lipase and fatty acid amide hydrolase.
References Cisneros, J.A. et al.: J. Med. Chem., 50, 5012 (2007); Stamatov, S. et al.: Tetrahed. Lett., 43, 1759 (2002);

Formula: C₂₃H₃₆O₃

Color and Shape: Neat

Molecular weight: 360.5301

Ref: TR-A765060

Arachidonic Acid Glycidyl Ester-d5

Controlled Product

CAS: 439146-24-4

Applications Labelled analogue of Arachidonic Acid Glycidyl Ester, an ester derivative of the essential fatty acid Arachidonic Acid (A765000) and an intermediate in the preparation of the endocannabinoid 2-Arachidonyl Glycerol (A765050). Arachidonic Acid Glycidyl Ester has inhibitory activity against monoacylglycerol lipase and fatty acid amide hydrolase.
References Cisneros, J.A. et al.: J. Med. Chem., 50, 5012 (2007); Stamatov, S. et al.: Tetrahed. Lett., 43, 1759 (2002);

Formula: C₂₃D₅H₃₁O₃

Color and Shape: Light Yellow

Molecular weight: 365.561

Ref: TR-A765062

O-Arachidonoyl glycidol

CAS: 439146-24-4

O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].

Formula: C₂₃H₃₆O₃

Color and Shape: Solid

Molecular weight: 360.53

Ref: TM-T84523