CAS 440-17-5: Trifluoperazine hydrochloride
Description:Trifluoperazine hydrochloride is a typical antipsychotic medication belonging to the phenothiazine class, primarily used in the treatment of schizophrenia and other psychotic disorders. It functions as a dopamine receptor antagonist, particularly targeting D2 receptors in the brain, which helps to alleviate symptoms such as hallucinations and delusions. The compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Its chemical structure includes a trifluoromethyl group, which contributes to its potency and efficacy. Trifluoperazine is also known for its sedative properties and may be used to manage anxiety and agitation. However, it can have side effects, including extrapyramidal symptoms, sedation, and potential cardiovascular effects. Due to its pharmacological profile, it is essential to monitor patients for adverse reactions and adjust dosages accordingly. As with all antipsychotics, the use of trifluoperazine should be carefully considered and managed by healthcare professionals.
Formula:C21H24F3N3S·2ClH
InChI:InChI=1S/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H
InChI key:InChIKey=BXDAOUXDMHXPDI-UHFFFAOYSA-N
SMILES:Cl.FC(F)(F)C1=CC=C2SC=3C=CC=CC3N(C2=C1)CCCN4CCN(C)CC4
- Synonyms:
- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluormethyl)-10H-phenothiazinhydrochlorid
- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride
- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine hydrochloride (1:1)
- 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine hydrochloride
- 10-[3-(4-méthylpipérazin-1-yl)propyl]-2-(trifluorométhyl)-10H-phénothiazine chlorhydrate
- 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride
- 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2)
- 10H-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:1)
- 10H-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, monohydrochloride
- 2-Trifluoromethyl-10-[3-(1-methyl-4-piperazinyl)propyl]phenothiazine dihydrochloride
- See more synonyms
- Eskazine
- Eskazinyl
- Fluoperazine
- Jatroneural
- Modalina
- Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride
- Skf 5019
- Stelazine
- Stellasil
- Terfluzine
- Trazine
- Trifluoperazine HCl
- Trifluoperazine dihydrochloride
- Trifluoperazine hydrochloride (VAN)
- Trifluoperazine hydrochloride [JAN]
- Trifluoroperazine dihydrochloride
- Trifluoroperazine hydrochloride
- Triftazin
- Triphthasine
- Triphthazine
- Triphthazine dihydrochloride
- Tryptazine
- Tryptazine dihydrochloride
- hydrogen chloride 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine (1:1:1)