CAS 440-17-5
:Trifluoperazine hydrochloride
Description:
Trifluoperazine hydrochloride is a typical antipsychotic medication belonging to the phenothiazine class, primarily used in the treatment of schizophrenia and other psychotic disorders. It functions as a dopamine receptor antagonist, particularly targeting D2 receptors in the brain, which helps to alleviate symptoms such as hallucinations and delusions. The compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Its chemical structure includes a trifluoromethyl group, which contributes to its potency and efficacy. Trifluoperazine is also known for its sedative properties and may be used to manage anxiety and agitation. However, it can have side effects, including extrapyramidal symptoms, sedation, and potential cardiovascular effects. Due to its pharmacological profile, it is essential to monitor patients for adverse reactions and adjust dosages accordingly. As with all antipsychotics, the use of trifluoperazine should be carefully considered and managed by healthcare professionals.
Formula:C21H24F3N3S·2ClH
InChI:InChI=1S/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H
InChI key:InChIKey=BXDAOUXDMHXPDI-UHFFFAOYSA-N
SMILES:C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(C(F)(F)F)C3.Cl
Synonyms:- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluormethyl)-10H-phenothiazinhydrochlorid
- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride
- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine hydrochloride (1:1)
- 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine hydrochloride
- 10-[3-(4-méthylpipérazin-1-yl)propyl]-2-(trifluorométhyl)-10H-phénothiazine chlorhydrate
- 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride
- 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2)
- 10H-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:1)
- 10H-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, monohydrochloride
- 2-Trifluoromethyl-10-[3-(1-methyl-4-piperazinyl)propyl]phenothiazine dihydrochloride
- Eskazine
- Eskazinyl
- Fluoperazine
- Jatroneural
- Modalina
- Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride
- Skf 5019
- Stelazine
- Stellasil
- Terfluzine
- Trazine
- Trifluoperazine HCl
- Trifluoperazine dihydrochloride
- Trifluoperazine hydrochloride (VAN)
- Trifluoperazine hydrochloride [JAN]
- Trifluoroperazine dihydrochloride
- Trifluoroperazine hydrochloride
- Triftazin
- Triphthasine
- Triphthazine
- Triphthazine dihydrochloride
- Tryptazine
- Tryptazine dihydrochloride
- See more synonyms
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Found 18 products.
Trifluoperazine Dihydrochloride
CAS:Formula:C21H24F3N3S·2HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:480.42Trifluoperazine Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS:Color and Shape:Single SolutionTrifluoperazine Hydrochloride
CAS:Antidepressants, tranquilizers and other pschotherapeutic agentsFormula:C21H24F3N3S·2HClColor and Shape:PowderMolecular weight:407.1643Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Formula:C21H26Cl2F3N3SPurity:99.57% - 99.96%Color and Shape:Cream Fine PowderMolecular weight:480.43Trifluoperazine dihydrochloride, EP grade
CAS:Formula:C21H24F3N3S·2HClPurity:99.0 - 101.0 % (dried substance)Color and Shape:White to pale yellow crystalline powderMolecular weight:480.42Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloridePurity:≥98%Molecular weight:480.43g/molTrifluoperazine DiHCl
CAS:Formula:C21H24F3N3S·2HClColor and Shape:White To Off-White SolidMolecular weight:407.50 2*36.46Trifluoperazine dihydrochloride
CAS:Formula:C21H24F3N3S·2HClPurity:98.0 - 101.0 % (dried basis)Color and Shape:Whtie to pale yellow crystalline powderMolecular weight:480.42Trifluoperazine dihydrochloride
CAS:Formula:C21H24F3N3SClHColor and Shape:NeatMolecular weight:480.42Trifluoperazine Hydrochloride
CAS:Controlled ProductFormula:C21H24F3N3SClHColor and Shape:NeatMolecular weight:480.42Trifluoperazine Dihydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Antipsychotic.<br>References Flanagan, T.L., et al.: J. Pharm. Sci., 51, 996 (1962), Post., A., et al.: Anal. Profiles Drug Subs., 9, 543 (1980)<br></p>Formula:C21H24F3N3S·2ClHColor and Shape:NeatMolecular weight:480.42Trifluoperazine dihydrochloride
CAS:Controlled Product<p>Trifluoperazine is a drug that belongs to the class of selective p-glycoprotein (p-gp) inhibitors. It has been shown to decrease cytosolic calcium levels and glucose-dependent insulinotropic peptide (glp-1) levels in rats. Trifluoperazine has also been shown to have constant pressure and physiological effects on energy metabolism in rat adipocytes at an optimum concentration of 1 μM. In addition, trifluoperazine inhibits the activity of target enzymes such as neuronal death and intracellular calcium levels. The optimal concentration for trifluoperazine is 1 μM, which can be determined by electrochemical impedance spectroscopy. Trifluoperazine also binds to fluorescence probes, which may be used for imaging purposes.</p>Formula:C21H26Cl2F3N3SPurity:(Titration) Min. 98.0%Color and Shape:PowderMolecular weight:480.42 g/molTrifluoperazine dihydrochloride
CAS:Formula:C21H26Cl2F3N3SPurity:≥98%(HPLC)(T)Molecular weight:479.118
