CAS 440124-96-9

Efavirenz Related Compound B ((S,E)-6-Chloro-4-(2-Cyclopropylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one)

CAS: 440124-96-9

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₄H₁₁ClF₃NO₂

Color and Shape: White Powder

Molecular weight: 317.04304

Ref: 45-1234147

Efavirenz USP Related Compound B

CAS: 440124-96-9

Formula: C₁₄H₁₁ClF₃NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 317.69

Ref: 4Z-E-074

(E)-Dihydro Efavirenz

CAS: 440124-96-9

Impurity Efavirenz USP Related Compound B
Applications (E)-Dihydro Efavirenz (Efavirenz USP Related Compound B) is an impurity of the nonnucleoside HIV-1 reverse transcriptase inhibitor Efavirenz (E425000).
References Weissburg, R.P. et al.: J. Pharmac. Biomed. Anal., 28, 45 (2002); Ribeiro, J.A.A. et al.: J. Pharmac. Biomed. Anal., 43, 298 (2007);

Formula: C₁₄H₁₁ClF₃NO₂

Color and Shape: Neat

Molecular weight: 317.69

Ref: TR-D448935

(4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

CAS: 440124-96-9

Efavirenz is a non-nucleoside reverse transcriptase inhibitor. It is used to treat HIV infection and AIDS. Efavirenz has been shown to be an impurity in the synthesis of 6-chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. The impurities are removed by a deprotection reaction that removes the protecting group from the molecule.

Formula: C₁₄H₁₁ClF₃NO₂

Purity: Min. 95%

Molecular weight: 317.69 g/mol

Ref: 3D-FC102842