CAS 440327-50-4

Guanosine, 2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-

Description:

Guanosine, 2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, identified by its CAS number 440327-50-4, is a modified nucleoside that features a guanine base linked to a ribose sugar, which is further substituted at the 2' position with a methoxyethyl group and at the nitrogen position with a 2-methyl-1-oxopropyl group. This structural modification can influence its biological activity, stability, and interaction with nucleic acids. Such modifications are often explored in the context of drug development, particularly for antiviral or anticancer therapies, as they may enhance the compound's pharmacokinetic properties or its ability to evade metabolic degradation. The presence of the methoxyethyl group can improve solubility and cellular uptake, while the oxopropyl moiety may contribute to specific binding interactions with target biomolecules. Overall, this compound exemplifies the ongoing efforts in medicinal chemistry to design nucleoside analogs with improved therapeutic profiles.

Formula: C₁₇H₂₅N₅O₇

N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine

CAS: 440327-50-4

Nucleoside Derivatives - 2’-Modified nucleosides;

Formula: C₁₇H₂₅N₅O₇

Color and Shape: Solid

Molecular weight: 411.41

Ref: TM-TNU0959

N2-Isobutyryl-2'-(2-methoxyethyl)guanosine

CAS: 440327-50-4

N2-Isobutyryl-2'-(2-methoxyethyl)guanosine is a nucleoside that is structurally related to guanosine. It is used as an activator for RNA synthesis and as a novel antiviral agent. This compound has been shown to have high purity, high quality, and excellent solubility. N2-Isobutyryl-2'-(2-methoxyethyl)guanosine has also been found to be active against HIV in vitro by inhibiting reverse transcriptase activity.

Purity: Min. 95%

Ref: 3D-NI138523