CAS 4412-93-5

7H-furo[2,3-f]chromen-7-one

Description:

7H-furo[2,3-f]chromen-7-one, also known as coumarin, is a chemical compound characterized by its fused furan and chromenone structure. It typically appears as a white to pale yellow crystalline solid and has a distinct sweet, vanilla-like odor. This compound is known for its aromatic properties and is commonly found in various plants, contributing to their fragrance. It exhibits a range of biological activities, including anticoagulant, anti-inflammatory, and antimicrobial effects, making it of interest in pharmaceutical research. The compound is soluble in organic solvents such as ethanol and ether but has limited solubility in water. Its chemical structure allows for various substitutions, leading to derivatives with enhanced properties. Additionally, 7H-furo[2,3-f]chromen-7-one is used in the production of perfumes, flavorings, and as a precursor in organic synthesis. However, it is important to note that some derivatives may pose health risks, necessitating careful handling and regulation in commercial applications.

Formula: C₁₁H₆O₃

InChI: InChI=1/C11H6O3/c12-10-4-2-8-9(14-10)3-1-7-5-6-13-11(7)8/h1-6H

SMILES: c1cc2c(ccc(=O)o2)c2c1cco2

Synonyms:

• 7H-Furo(2,3-f)(1)benzopyran-7-one

Bakuchicin

CAS: 4412-93-5

Lactone

Formula: C₁₁H₆O₃

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 186.17

Ref: 5G-89578

Bakuchicin

Controlled Product

CAS: 4412-93-5

Formula: C₁₁H₆O₃

Color and Shape: Neat

Molecular weight: 186.163

Ref: TR-B445200

Bakuchicin

CAS: 4412-93-5

Bakuchicin is a plant-derived molecule that inhibits the activity of topoisomerase II, which is an enzyme involved in DNA replication. Bakuchicin has shown antiviral properties in vitro and in vivo against human viruses, such as hepatitis B virus (HBV), by inhibiting viral RNA replication. Bakuchicin also affects the production of pro-inflammatory cytokines and has been shown to have antidepressant effects in mice. The mechanism of action of bakuchicin is not yet fully understood; however, it may be due to its inhibition of topoisomerase II, leading to dna replication inhibition and subsequent depression in mice.

Formula: C₁₁H₆O₃

Purity: Min. 95%

Molecular weight: 186.16 g/mol

Ref: 3D-EAA41293