CAS 441785-25-7: Besifovir

Description: Besifovir is an antiviral compound primarily investigated for its potential use in the treatment of hepatitis B virus (HBV) infections. It belongs to the class of nucleoside analogs, which function by inhibiting viral replication. The chemical structure of besifovir features a modified nucleoside backbone, which enhances its efficacy against HBV. Its mechanism of action involves the selective inhibition of the viral polymerase, thereby disrupting the viral life cycle. Besifovir has demonstrated a favorable pharmacokinetic profile, including good oral bioavailability and a long half-life, which supports its potential for once-daily dosing. Additionally, it has shown a lower propensity for developing resistance compared to some other antiviral agents. Safety and tolerability studies indicate that besifovir may have a manageable side effect profile, although ongoing clinical trials are essential to fully establish its therapeutic potential and long-term effects. Overall, besifovir represents a promising candidate in the ongoing search for effective treatments for chronic hepatitis B infection.

Formula: C₁₀H₁₄N₅O₄P

InChI: InChI=1S/C10H14N5O4P/c11-9-12-3-7-8(14-9)15(5-13-7)4-10(1-2-10)19-6-20(16,17)18/h3,5H,1-2,4,6H2,(H2,11,12,14)(H2,16,17,18)

InChI key: InChIKey=KDNSSKPZBDNJDF-UHFFFAOYSA-N

SMILES: O=P(O)(O)COC1(CN2C=NC=3C=NC(=NC32)N)CC1

Synonyms:

• ((1-((2-Amino-9H-purin-9-yl)methyl)cyclopropoxy)methyl)phosphonic acid
• ((1-((2-Amino-9H-purin-9-yl)methyl)cyclopropoxy)methyl)phosphonicacid
• Besifovir
• Lb-80331
• P-[[[1-[(2-Amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]phosphonic acid
• Phosphonic acid, P-[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]-
• Phosphonic acid, [[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]-
• [({1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl}oxy)methyl]phosphonic acid
• Phosphonic Acid, [[[1-[(2-Amino-9h-Purin-9-Yl)Methyl]Cyclopropyl]Oxy]Methyl]-(9ci)

PHOSPHONIC ACID, [[[1-[(2-AMINO-9H-PURIN-9-YL)METHYL]CYCLOPROPYL]OXY]METHYL]- (9CI)

CAS: 441785-25-7

• Formula: C₁₀H₁₄N₅O₄P
• Purity: %
• Color and Shape: Solid
• Molecular weight: 299.223

Besifovir

CAS: 441785-25-7

• Purity: 98%
• Molecular weight: 299.22g/mol

Besifovir

CAS: 441785-25-7

Besifovir 是由 LB80380 转化而来的一种 LB80380 母体药物,进一步代谢为其活性形式 LB80317。LB80380 是抗乙型肝炎病毒的抗病毒药物。

• Formula: C₁₀H₁₄N₅O₄P
• Purity: ≥95%
• Color and Shape: Solid
• Molecular weight: 299.22

Besifovir

CAS: 441785-25-7

Besifovir is an antiviral drug used to treat chronic hepatitis B. It inhibits viral replication …

• Formula: C₁₀H₁₄N₅O₄P
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 299.22 g/mol