CAS 442-16-0

Ethacridine

Description:

Ethacridine, with the CAS number 442-16-0, is an organic compound belonging to the acridine family. It is characterized by its aromatic structure, which includes a tricyclic ring system. Ethacridine is primarily known for its antiseptic properties and has been used in medical applications, particularly as a topical antiseptic and in certain formulations for treating infections. The compound exhibits a yellow to orange color and is soluble in organic solvents but has limited solubility in water. Ethacridine functions by disrupting microbial cell membranes and inhibiting nucleic acid synthesis, making it effective against a range of bacteria. Additionally, it has been studied for its potential use in cancer therapy due to its ability to intercalate with DNA. However, its use is subject to regulatory scrutiny, and safety profiles must be considered, as it can exhibit cytotoxic effects at higher concentrations. Overall, ethacridine is a versatile compound with significant applications in both medicinal chemistry and microbiology.

Formula: C₁₅H₁₅N₃O

InChI: InChI=1S/C15H15N3O/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13/h3-8H,2,16H2,1H3,(H2,17,18)

InChI key: InChIKey=CIKWKGFPFXJVGW-UHFFFAOYSA-N

SMILES: NC=1C2=C(N=C3C1C=CC(N)=C3)C=CC(OCC)=C2

Synonyms:

• 2,5-Diamino-7-ethoxyacridine
• 2-Ethoxy-6,9-acridinediamine
• 2-Ethoxy-6,9-diaminoacridine
• 3,9-Acridinediamine, 7-ethoxy-
• 3,9-Acridinediamine, 7-ethoxy- (9CI)
• 6,9-Diamino-2-ethoxyacridine
• 7-Ethoxy-3,9-acridinediamine
• 7-Ethoxy-3,9-diaminoacridine
• Acridine, 6,9-diamino-2-ethoxy-
• Acridine, 6,9-diamino-2-ethoxy- (8CI)
• Aethacridinum
• Etacridina
• Etacridina [INN-Spanish]
• Etakridin
• Ethacridine [INN:BAN]
• Ethacridinum
• Ethacridinum [INN-Latin]
• Nsc 163296
• Unii-Wix85M1A6R
• Ethacridine

2-ETHOXY-6,9-DIAMINOACRIDINE

CAS: 442-16-0

Formula: C₁₅H₁₅N₃O

Purity: 97%

Molecular weight: 253.2991

Ref: IN-DA00D9JZ

Ethacridine

CAS: 442-16-0

Formula: C₁₅H₁₅N₃O

Molecular weight: 253.31

Ref: 4Z-E-199001

Ethacridine

CAS: 442-16-0

Ethacridine acts as an inhibitor of poly (ADP-ribose) glycohydrolase (PARG) and functions as an activator of transcriptional coactivators. It induces apoptosis in thyroid cancer cells and promotes the differentiation of thyroid follicular cells.

Formula: C₁₅H₁₅N₃O

Color and Shape: Solid

Molecular weight: 253.30

Ref: TM-T88097