CAS 442-51-3
:Harmine derivative
Description:
Harmine derivative, identified by the CAS number 442-51-3, is a compound related to harmine, which is a beta-carboline alkaloid. This substance exhibits several notable characteristics, including its role as a reversible inhibitor of monoamine oxidase A (MAO-A), which is significant in the context of neuropharmacology and potential therapeutic applications. Harmine derivatives are often studied for their psychoactive properties and potential use in treating various mental health disorders. They may also exhibit antioxidant and anti-inflammatory activities, contributing to their interest in medicinal chemistry. Structurally, harmine derivatives typically contain a fused indole and pyridine ring system, which is crucial for their biological activity. Additionally, these compounds can interact with various neurotransmitter systems, influencing mood and cognition. The study of harmine derivatives continues to evolve, with ongoing research exploring their pharmacological potential and mechanisms of action in the central nervous system.
Formula:C13H12N2O
InChI:InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
InChI key:InChIKey=BXNJHAXVSOCGBA-UHFFFAOYSA-N
SMILES:CC1=C2C(C=3C(N2)=CC(OC)=CC3)=CC=N1
Synonyms:- 1-Methyl-7-methoxy-β-carboline
- 7-Methoxy-1-methyl-9H-beta-carbolin
- 7-Methoxy-1-methyl-9H-beta-carboline
- 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole
- 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-
- Banisterin
- Banisterine
- Banisterine Monohydrate
- Harmin
- Harmine
- Leucoharmine
- Telepathin
- Telepathine
- Yagein
- Yageine
- 4-b)indole,7-methoxy-1-methyl-9h-pyrido(
- TELEPATHINE MONOHYDRATE
- 1-Methyl-7-methoxy-beta-carboline
- Telepathien
- PYRIDO(3,4-B)INDOLE,7-METHOXY-1-METHYL-
- Harmine,98+%
- HARMINE FREE BASE
- Garmin
- HARMINE MONOHYDRATE
- HARMAN MONOHYDROCHLORIDE MONOHYDRATE
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 13 products.
Harmine
CAS:Formula:C13H12N2OPurity:>98.0%(T)Color and Shape:White to Orange to Green powder to crystalMolecular weight:212.259H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-
CAS:Formula:C13H12N2OPurity:98%Color and Shape:SolidMolecular weight:212.2472Harmine
CAS:Formula:C13H12N2OPurity:97.5 - 102.5 %Color and Shape:White to off-white crystalline powderMolecular weight:212.25Harmine
CAS:<p>Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.</p>Formula:C13H12N2OPurity:98.29% - 99.92%Color and Shape:Off-White SolidMolecular weight:212.25Harmine
CAS:Natural alkaloidFormula:C13H12N2OPurity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:212.25Harmine
CAS:<p>Applications Harmine is a natural β-carboline alkaloid and a CNS stimulant (1,2). Harmine has been shown to be a potent and selective inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) (3). DYRK1A is a potential therapeutic target for treating diabetes, Down Syndrome, and HIV (4).<br>References (1) DiStefano, S., et al.: J. Pharmacol. Exp. Ther., 174, 456 (1970)(2) Dos Santos, R. G. and Hallak, J. E. J Psychoactive Drugs. 5,1 (2016) (3) Atteya, R., et al.: Mech Ageing Dev. 6, S0047 (2016)(4) Bol, S. M., et al.: PLoS One. 6, e17190 (2011)<br></p>Formula:C13H12N2OColor and Shape:White To BrownMolecular weight:212.25Harmine
CAS:Controlled Product<p>Harmine is a molecule that interacts with DNA by binding to the minor groove, which is the non-helical area of DNA. Harmine has been shown to have cytotoxic properties in murine hepatoma cells, as well as anticancer activity in mouse tumor cells. Harmine also has antiviral and antimicrobial effects, and has been shown to inhibit the growth of human cancer cells. Harmine binds to Toll-like receptor 4 (TLR4), which is a pattern recognition receptor that plays an important role in innate immunity. Harmine inhibits TLR4 signaling, thereby inhibiting inflammatory responses such as acute toxicities. The molecular docking analysis of harmine shows that it has high affinity for polymerase chain reaction (PCR) enzymes and can be used for PCR inhibition studies. The analytical method for harmine was developed using a natural compound crystal structure as a model system.</p>Formula:C13H12N2OMolecular weight:212.25 g/molHarmine
CAS:Formula:C13H12N2OPurity:99%Color and Shape:Solid, Very pale yellow to pale yellow powderMolecular weight:212.252
![9H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00I8E6.jpg&w=3840&q=75)
