CAS 443-72-1

N6-Methyladenine

Description:

N6-Methyladenine is a derivative of adenine, a purine nucleobase that plays a crucial role in various biological processes, including DNA and RNA synthesis. This compound is characterized by the presence of a methyl group attached to the nitrogen atom at the sixth position of the adenine ring structure. It is a white to off-white solid that is soluble in polar solvents such as water and methanol. N6-Methyladenine is known to participate in various biochemical pathways and has been studied for its potential roles in gene regulation and cellular signaling. Its structural modification can influence the stability and function of nucleic acids, making it a subject of interest in molecular biology and biochemistry. Additionally, N6-Methyladenine has been implicated in epigenetic regulation, as it can affect the expression of genes by modifying chromatin structure. Overall, this compound serves as an important tool for researchers exploring the complexities of genetic regulation and cellular processes.

Formula: C₆H₇N₅

InChI: InChI=1S/C6H7N5/c1-7-5-4-6(10-2-8-4)11-3-9-5/h2-3H,1H3,(H2,7,8,9,10,11)

InChI key: InChIKey=CKOMXBHMKXXTNW-UHFFFAOYSA-N

SMILES: N(C)C1=C2C(N=CN2)=NC=N1

Synonyms:

• 1H-Purin-6-amine, N-methyl-
• 6-(N-Methylamino)purine
• 6-Map
• 6-Methyladenine
• 6-Methylaminopurine
• 6-Mono(methylamino)purine
• 6-N-Methyladenine
• 9H-Purin-6-amine, N-methyl-
• Adenine, N-methyl-
• Methyl(Purin-6-Yl)Amine
• N-Methyl-6-aminopurine
• N-Methyl-9H-purin-6-amine
• N-methyl-5H-purin-6-amine
• N-methyl-7H-purin-6-amine
• N6-Methylademine
• N6-Methyladenine
• N⁶-Methyladenine
• N⁶-Methylaminopurine
• N⁶-Monomethyladenine

1H-Purin-6-amine, N-methyl-

CAS: 443-72-1

Formula: C₆H₇N₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 149.1533

Ref: IN-DA00I8EJ

6-(Methylamino)purine

CAS: 443-72-1

6-(Methylamino)purine

Purity: 97%

Molecular weight: 149.15g/mol

Ref: 54-OR930003

N6-Methyladenine

CAS: 443-72-1

N6-Methyladenine

Purity: ≥98%

Molecular weight: 149.15g/mol

Ref: 54-BUP13856

N6-Methyladenine

CAS: 443-72-1

N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.

Formula: C₆H₇N₅

Purity: 99.78%

Color and Shape: Solid

Molecular weight: 149.15

Ref: TM-T36572

N-Methyl-7H-purin-6-amine

CAS: 443-72-1

Formula: C₆H₇N₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 149.16

Ref: 3B-M3166

6-(Methylamino)purine

Controlled Product

CAS: 443-72-1

Applications 6-(Methylamino)purine, 6-methylade is a reagent for substitution of adenine nucleotide analogs containing bicyclohexane ring system locked in northern conformation enhanced potency as py receptor antagonists. Adenine methylation as an epigenic mark has been observed in single-celled organisms and also rarely in mamalian cells.
References Nandanan et al.: J. Med. Chem., 43, 829 (2000); Kim, H. S. et al.: J. Med. chem., 46, 4974 (2003); Chem. and Eng. News p.6 Apr. 4 (2016)

Formula: C₆H₇N₅

Color and Shape: Neat

Molecular weight: 149.15

Ref: TR-M287005

N-Methyl-7H-purin-6-amine

CAS: 443-72-1

Formula: C₆H₇N₅

Purity: 95%

Color and Shape: Liquid, No data available.

Molecular weight: 149.157

Ref: 10-F463038

6-(Methylamino)purine-13C2,15N

Controlled Product

CAS: 443-72-1

Formula: C₂C₄H₇₁₅NN₄

Color and Shape: Neat

Molecular weight: 152.132

Ref: TR-M287007

6-(Methylamino)purine-d3

Controlled Product

CAS: 443-72-1

Formula: C₆D₃H₄N₅

Color and Shape: Neat

Molecular weight: 152.172

Ref: TR-M287008

N6-Methyladenine

CAS: 443-72-1

N6-Methyladenine is a modification of adenine in DNA. It is formed by the methylation of the N6 position of adenine, which is a group P2 purine base. The structural analysis of this compound has been studied using x-ray diffraction data, and it has been found that it may inhibit cancer cells by modifying their DNA. This compound can also be used as an antimicrobial agent to treat infections caused by eukaryotes such as bacteria and fungi. N6-Methyladenine may be useful in transcriptional regulation and cellular transformation.

Formula: C₆H₇N₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 149.15 g/mol

Ref: 3D-FM10151