CAS 4431-01-0

Ligustilide

Description:

Ligustilide is a natural compound primarily found in various plants, particularly in the roots of Angelica species, such as Angelica gigas and Angelica sinensis. It is classified as a phthalide, which is a type of cyclic compound featuring a lactone structure. Ligustilide is known for its characteristic aromatic properties and has been studied for its potential pharmacological effects, including anti-inflammatory, antioxidant, and neuroprotective activities. The compound exhibits a pleasant, sweet, and slightly spicy aroma, making it of interest in the fragrance and flavor industries. Ligustilide is also recognized for its role in traditional medicine, particularly in East Asian herbal practices. Its solubility is generally higher in organic solvents than in water, which influences its extraction and application in various formulations. Additionally, research continues to explore its mechanisms of action and potential therapeutic uses, highlighting its significance in both natural product chemistry and medicinal applications.

Formula: C₁₂H₁₄O₂

InChI: InChI=1S/C12H14O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h5,7-8H,2-4,6H2,1H3

InChI key: InChIKey=IQVQXVFMNOFTMU-UHFFFAOYSA-N

SMILES: C(CCC)=C1C2=C(C(=O)O1)C=CCC2

Synonyms:

• (3Z)-3-butylidene-4,5-dihydro-2-benzofuran-1(3H)-one
• 1(3H)-Isobenzofuranone, 3-butylidene-4,5-dihydro-
• 1,5-Cyclohexadiene-1-carboxylic acid, 2-(1-hydroxy-1-pentenyl)-, γ-lactone
• 1-ethyl-1-methyl-1,1a,6,7-tetrahydrocyclopropa[c][2]benzofuran-3(3aH)-one
• 3-Butylidene-4,5-dihydro-1(3H)-isobenzofuranone
• 3-Butylidene-4,5-dihydro-2-benzofuran-1-one
• 3-Butylidene-4,5-dihydrophthalide
• Angelica Sinensis Extract
• Angelica extract
• Phthalide, 3-butylidene-4,5-dihydro-
• Ligustilide

Ligustilide

CAS: 4431-01-0

Ligustilide

Purity: ≥95%

Molecular weight: 190.24g/mol

Ref: 54-BUP04643

Ligustilide

CAS: 4431-01-0

Formula: C₁₂H₁₄O₂

Molecular weight: 190.24

Ref: 4Z-C-1642

Ligustilide

CAS: 4431-01-0

3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.

Formula: C₁₂H₁₄O₂

Purity: 96.03% - 98.14%

Color and Shape: Yellow Brown Powder

Molecular weight: 190.24

Ref: TM-T5S1287

Ligustilide-d7

CAS: 4431-01-0

Formula: C₁₂H₇D₇O₂

Molecular weight: 197.28

Ref: 4Z-C-1645

Z-Ligustilide

CAS: 4431-01-0

Z-Ligustilide is a bioactive compound, which is a naturally occurring phthalide derivative extracted from the roots of Angelica sinensis. It is primarily known for its presence in traditional Chinese medicinal herbs such as Dong Quai (Angelica sinensis), where it acts as one of the major active constituents.

Formula: C₁₂H₁₄O₂

Purity: Min. 98 Area-%

Color and Shape: Slightly Yellow Clear Liquid

Molecular weight: 190.24 g/mol

Ref: 3D-FL40394

Ligustilide

Controlled Product

CAS: 4431-01-0

Stability Light Sensitive
Applications Ligustilide, is a dihydrophthalide, and an active ingredients of umbelliferous plants as Angelica sinensis and Ligusticum chuanxiong, having wide range of pharmacology effects on neuroprotection, vasodilatation, anti-caner and anti-tumor, analgesia and anti-inflammation.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zuo, A., et al.: Zhongguo Zhongyao Zazhi, 37, 3350 (2012); Long, R., et al.: Tropical J. Pharmac. Res., 11, 421 (2012);

Formula: C₁₂H₁₄O₂

Color and Shape: Colourless

Molecular weight: 190.24

Ref: TR-L397900

Ligustilide

CAS: 4431-01-0

Formula: C₁₂H₁₄O₂

Purity: >95.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 190.24

Ref: 3B-L0385