CAS 4433-40-3

5-(Hydroxymethyl)uracil

Description:

5-(Hydroxymethyl)uracil is a pyrimidine derivative and a modified form of uracil, which is one of the four nucleobases in RNA. This compound features a hydroxymethyl group (-CH2OH) at the 5-position of the uracil ring, which alters its chemical properties and biological activity. It is typically a white to off-white solid and is soluble in polar solvents like water and alcohols, owing to the presence of the hydroxymethyl group. This modification can influence its interactions with nucleic acids and enzymes, potentially affecting its role in biological systems. 5-(Hydroxymethyl)uracil is of interest in biochemical research and may have applications in the development of pharmaceuticals or as a biochemical probe. Its structure allows for hydrogen bonding and potential participation in various chemical reactions, making it a subject of study in medicinal chemistry and molecular biology. As with many chemical substances, handling should be done with care, following appropriate safety protocols.

Formula: C₅H₆N₂O₃

InChI: InChI=1S/C5H6N2O3/c8-2-3-1-6-5(10)7-4(3)9/h1,8H,2H2,(H2,6,7,9,10)

InChI key: InChIKey=JDBGXEHEIRGOBU-UHFFFAOYSA-N

SMILES: C(O)C=1C(=O)NC(=O)NC1

Synonyms:

• 2,4(1H,3H)-Pyrimidinedione, 5-(hydroxymethyl)-
• 4-Methyl-5-oxyuracil
• 5-(Hydroxymethyl)-1,3-dihydropyrimidine-2,4-dione
• 5-(Hydroxymethyl)-2,4(1H,3H)-pyrimidinedione
• 5-(Hydroxymethyl)pyrimidine-2,4-dione~Uracil-5-methanol
• 5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione
• 5-Hydroxymethyl-1H-pyrimidine-2,4-dione
• 5-Hydroxymethyluracil
• NSC 20901
• Uracil, 5-(hydroxymethyl)-
• α-Hydroxythymine

5-(Hydroxymethyl)pyrimidine-2,4(1H,3H)-dione

CAS: 4433-40-3

Formula: C₅H₆N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 142.1127

Ref: IN-DA003MSU

5-Hydroxymethyluracil

CAS: 4433-40-3

5-Hydroxymethyluracil

Purity: ≥95%

Molecular weight: 142.11g/mol

Ref: 54-BUP18590

5-(Hydroxymethyl)uracil

CAS: 4433-40-3

5-(Hydroxymethyl)uracil

Formula: C₅H₆N₂O₃

Purity: ≥95%

Color and Shape: white solid

Molecular weight: 142.11g/mol

Ref: 54-OR4151

5-Hydroxymethyluracil

CAS: 4433-40-3

Formula: C₅H₆N₂O₃

Purity: ≥ 95.0%

Color and Shape: White to off-white powder

Molecular weight: 142.12

Ref: 7W-GN9534

5-Hydroxymethyluracil

CAS: 4433-40-3

Formula: C₅H₆N₂O₃

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 142.11

Ref: 3B-H1323

5-Hydroxymethyluracil

CAS: 4433-40-3

5-Hydroxymethyluracil (a-Hydroxythymine) is an oxidation damage product derived from thymine or 5-methylcytosine and is a product of thymine dioxygenase.

Formula: C₅H₆N₂O₃

Purity: 97.3%

Color and Shape: Solid

Molecular weight: 142.11

Ref: TM-T5255

5-Hydroxymethyluracil

Controlled Product

CAS: 4433-40-3

Applications 5-Hydroxymethyluracil (cas# 4433-40-3) is a compound useful in organic synthesis.

Formula: C₅H₆N₂O₃

Color and Shape: Neat

Molecular weight: 142.11

Ref: TR-H948375

5-(Hydroxymethyl)pyrimidine-2,4(1H,3H)-dione

CAS: 4433-40-3

Formula: C₅H₆N₂O₃

Purity: 95%

Color and Shape: Solid, Powder

Molecular weight: 142.114

Ref: 10-F220269

5-Hydroxymethyluracil

CAS: 4433-40-3

5-Hydroxymethyluracil is a precursor of thymine and uracil. It is used as a therapeutic agent to prevent the formation of thymine dimers in human cells that have been exposed to radiation. 5-Hydroxymethyluracil is also used for the treatment of hyperuricemia and gout, as well as for the prevention and treatment of thrombotic disorders. 5-Hydroxymethyluracil is metabolized by hydroxylation, deamination, and oxidation to form xanthine, hypoxanthine, or uric acid. The most common analytical procedure for measuring plasma levels of 5-hydroxymethyluracil is mass spectrometry (MS). MS can be used in conjunction with polymerase chain reaction (PCR) to identify mutations in wild-type strains of bacteria.

Formula: C₅H₆N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 142.11 g/mol

Ref: 3D-FH10457

5-(Hydroxymethyl)uracil, 98%

CAS: 4433-40-3

5-(Hydroxymethyl)uracil serves as a stable major oxidative modification of thymine formed through the action of ionizing radiation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy

Formula: C₅H₆N₂O₃

Purity: 98%

Color and Shape: White to cream or grey, Powder

Molecular weight: 142.11

Ref: 02-L01682