CAS 443642-33-9

7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-7-(2-C-methyl-b-D-ribofuranosyl)-

Description:

7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-(2-C-methyl-b-D-ribofuranosyl)-, identified by CAS number 443642-33-9, is a chemical compound that features a fused bicyclic structure comprising a pyrrole and a pyrimidine ring. This compound is characterized by the presence of a chlorine atom at the 4-position and a ribofuranosyl moiety at the 7-position, which contributes to its biological activity. The C-methyl substitution on the ribofuranosyl group enhances its stability and solubility in biological systems. This compound is of interest in medicinal chemistry, particularly for its potential antiviral and anticancer properties, as it may interact with nucleic acid synthesis pathways. Its structural features suggest that it could act as a nucleoside analog, which is a common strategy in drug design to inhibit viral replication or cancer cell proliferation. The compound's unique structure and functional groups make it a subject of research for developing new therapeutic agents.

Formula: C₁₂H₁₄ClN₃O₄

Synonyms:

• 4-Chloro-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-Pyrrolo[2,3-d]pyrimidine

4-Chloro-7-(2-C-methyl-β-D-ribofuranosyl)-7H-Pyrrolo[2,3-d]pyrimidine

CAS: 443642-33-9

Ref: 7W-GN9996

4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]   pyrimidine

CAS: 443642-33-9

4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-

Formula: C₁₂H₁₄ClN₃O₄

Color and Shape: Solid

Molecular weight: 299.71

Ref: TM-TNU0102

4-Chloro-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Controlled Product

CAS: 443642-33-9

Formula: C₁₂H₁₄ClN₃O₄

Color and Shape: Neat

Molecular weight: 299.71

Ref: TR-C210610

4-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

CAS: 443642-33-9

4-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a novel anticancer compound that inhibits the synthesis of DNA, RNA and protein. It is a phosphoramidite monophosphate that can be used in the synthesis of oligonucleotides and DNA. 4CHP is effective against Herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). 4CHP also has antiviral activity against influenza A virus.

Formula: C₁₂H₁₄ClN₃O₄

Purity: Min. 95%

Molecular weight: 299.71 g/mol

Ref: 3D-NC14084