CAS 443642-38-4

4H-Pyrrolo[2,3-d]pyrimidin-4-one,2-amino-1,7-dihydro-7-(2-C-methyl-b-D-ribofuranosyl)- (9CI)

Description:

4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-1,7-dihydro-7-(2-C-methyl-b-D-ribofuranosyl)-, commonly referred to by its CAS number 443642-38-4, is a chemical compound characterized by its unique bicyclic structure that incorporates both pyrrole and pyrimidine rings. This compound features a 2-amino group and a ribofuranosyl moiety, which contributes to its potential biological activity. It is often studied for its role in medicinal chemistry, particularly in the development of antiviral and anticancer agents. The presence of the C-methyl group on the ribofuranosyl unit enhances its stability and bioavailability. The compound's molecular structure allows for various interactions with biological targets, making it a subject of interest in pharmacological research. Additionally, its solubility and reactivity can vary based on the functional groups present, influencing its application in drug design and synthesis. Overall, this compound exemplifies the complexity and diversity of nucleoside analogs in therapeutic development.

Formula: C₁₂H₁₆N₄O₅

Synonyms:

• 7-Deaza-2'-C-methylguanosine
• 2-Amino-1,7-Dihydro-7-(2-C-Methyl-Beta-D-Ribofuranosyl)-4H-Pyrrolo[2,3-D]Pyrimidin-4-One

2-Amino-7-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

CAS: 443642-38-4

Formula: C₁₂H₁₆N₄O₅

Molecular weight: 296.2792

Ref: IN-DA00DA4F

7-Deaza-2''-C-methylguanosine

CAS: 443642-38-4

Ref: 7W-GN6516

7-Deaza-2'-C-methylguanosine

CAS: 443642-38-4

7-Deaza-2'-C-methylguanosine is a nucleoside that is obtained from the synthesis of 7-deazaguanosine. It has antiviral activity and has been shown to be an activator for DNA synthesis. This compound is used as a monophosphate, diphosphate, or phosphoramidite in the synthesis of oligonucleotides. 7-Deaza-2'-C-methylguanosine has been shown to have anticancer properties, which may be due to its ability to inhibit ribonucleotide reductase and thus inhibit DNA synthesis.

Formula: C₁₂H₁₆N₄O₅

Purity: Min. 95%

Molecular weight: 296.29 g/mol

Ref: 3D-ND08382