CAS 443642-48-6

7H-Pyrrolo[2,3-d]pyrimidin-2-amine,7-(2-C-methyl-b-D-ribofuranosyl)-

Description:

7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 7-(2-C-methyl-b-D-ribofuranosyl)-, identified by its CAS number 443642-48-6, is a chemical compound that features a pyrrolo-pyrimidine core structure, which is significant in medicinal chemistry due to its potential biological activity. This compound includes a ribofuranosyl moiety, which is a sugar component that can enhance the compound's solubility and bioavailability. The presence of the amino group at the 2-position of the pyrimidine ring suggests potential for hydrogen bonding and interaction with biological targets, making it of interest in drug development. The C-methyl modification on the ribofuranosyl unit may influence the compound's pharmacokinetics and pharmacodynamics. Overall, this compound's unique structural features may contribute to its potential applications in therapeutic contexts, particularly in the development of antiviral or anticancer agents, although specific biological activities would require further investigation through experimental studies.

Formula: C₁₂H₁₆N₄O₄

Synonyms:

• 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

CAS: 443642-48-6

Ref: 7W-GN9318

7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

CAS: 443642-48-6

7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (Ampyra) is a synthetic nucleoside activator of the deoxyribonucleoside monophosphate (dNMP) and dNMP diphosphate (dNDP) pathways. It has antiviral and anticancer activities, as well as an inhibitory effect on DNA synthesis by blocking the polymerization of deoxyribonucleotides.
It is also an inhibitor of histone acetyltransferase and may be useful in the treatment of Alzheimer's disease. Ampryra is a novel compound with high purity and high quality. It is phosphoramidite that can be used for the preparation of oligodeoxynucleotides for use in DNA sequencing or gene therapy.

Purity: Min. 95%

Ref: 3D-NM14094