CAS 443642-53-3

7H-Pyrrolo[2,3-d]pyrimidin-4-amine,5-methyl-7-(2-C-methyl-b-D-ribofuranosyl)-

Description:

7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-methyl-7-(2-C-methyl-b-D-ribofuranosyl)-, identified by CAS number 443642-53-3, is a complex organic compound that features a fused pyrrole and pyrimidine ring system. This structure contributes to its potential biological activity, particularly in the context of nucleoside analogs. The presence of the 2-C-methyl-β-D-ribofuranosyl moiety suggests that it may interact with nucleic acids or enzymes involved in nucleic acid metabolism. The compound is characterized by its nitrogen-rich heterocyclic framework, which can influence its solubility, stability, and reactivity. Additionally, the methyl groups on the pyrimidine ring may enhance its lipophilicity, potentially affecting its pharmacokinetic properties. Such compounds are often investigated for their roles in medicinal chemistry, particularly as antiviral or anticancer agents, due to their ability to mimic natural nucleosides. Overall, this substance exemplifies the intricate relationship between molecular structure and biological function in the realm of pharmaceutical chemistry.

Formula: C₁₃H₁₈N₄O₄

Synonyms:

• 5-methyl-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

5-Methyl-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAS: 443642-53-3

Ref: 7W-GN6931

5-Methyl-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAS: 443642-53-3

5-Methyl-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a synthetic nucleoside analog of 2'-deoxyadenosine. It is an activator of DNA synthesis and replication by virtue of its ability to inhibit the enzyme ribonucleotide reductase. The compound has antiviral and anticancer activities, as well as antitumor activity. 5-Methyl-7-(2-C-methyl-b-Dribofuranosyl)-7H-[1,2] pyrrolo[2,3]-d]pyrimidin--4--amine has shown good results in treating chronic myelogenous leukemia.

Formula: C₁₃H₁₈N₄O₄

Purity: Min. 95%

Molecular weight: 294.31 g/mol

Ref: 3D-NM14093