CAS 444-27-9

4-Thiazolidinecarboxylic acid

Description:

4-Thiazolidinecarboxylic acid, with the CAS number 444-27-9, is a heterocyclic organic compound characterized by a five-membered ring containing both sulfur and nitrogen atoms. This compound features a carboxylic acid functional group, which contributes to its acidic properties. It is typically a white to off-white crystalline solid that is soluble in water and polar organic solvents, reflecting its polar functional groups. The presence of the thiazolidine ring imparts unique reactivity, making it of interest in various chemical syntheses and biological applications. 4-Thiazolidinecarboxylic acid can participate in reactions typical of carboxylic acids, such as esterification and amidation, and may also engage in nucleophilic substitution due to the presence of the sulfur atom. Its derivatives have been studied for potential pharmacological activities, including antimicrobial and anti-inflammatory properties. Overall, this compound serves as a valuable building block in organic synthesis and medicinal chemistry.

Formula: C₄H₇NO₂S

InChI: InChI=1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)

InChI key: InChIKey=DZLNHFMRPBPULJ-UHFFFAOYSA-N

SMILES: C(O)(=O)C1CSCN1

Synonyms:

• 1,3-Thiazolane-4-carboxylic acid
• 1,3-Thiazolidin-3-ium-4-carboxylate
• 1,3-Thiazolidine-4-carboxylic acid
• 3-Thioxoproline
• 4-Carboxythiazolidine
• 4-Thiazolidinecarboxylic acid
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-4-Thiazolidinecarboxylic acid
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Thiaproline
• DL-Thiaproline
• Detoxepa
• Hepalidine
• Heparegen
• Heparegene
• Norgamem
• Norgamen
• Nsc 25855
• T 4Ca
• Thiaproline
• Thiazolidine-4-Carboxylic Acid
• Thiazolidinecarboxylic acid
• Thioproline
• Tiazolidin
• g-Thiaproline

Timonacic

CAS: 444-27-9

Timonacic (Thioproline) has been used in trials studying the treatment of HIV Infections.

Formula: C₄H₇NO₂S

Purity: 99.99%

Color and Shape: Solid

Molecular weight: 133.17

Ref: TM-T0221

4-​Thiazolidinecarboxyl​ic acid

CAS: 444-27-9

Formula: C₄H₇NO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 133.1689

Ref: IN-DA002U39

Thiazolidine-4-Carboxylic Acid

CAS: 444-27-9

Thiazolidine-4-Carboxylic Acid

Purity: 98%

Molecular weight: 133.17g/mol

Ref: 54-OR1030364

Timonacic

CAS: 444-27-9

Timonacic

Purity: ≥98%

Molecular weight: 133.17g/mol

Ref: 54-BUP17655

Timonacic-13C-d2

CAS: 444-27-9

Formula: C₃₁₃CH₅D₂NO₂S

Molecular weight: 136.17

Ref: 4Z-C-4113

Timonacic-d2

CAS: 444-27-9

Formula: C₄H₅D₂NO₂S

Molecular weight: 135.18

Ref: 4Z-C-4112

Timonacic

CAS: 444-27-9

Formula: C₄H₇NO₂S

Molecular weight: 133.17

Ref: 4Z-C-4111

Timonacic-d4

Controlled Product

CAS: 444-27-9

Formula: C₄D₄H₃NO₂S

Color and Shape: Neat

Molecular weight: 137.194

Ref: TR-T443736

Timonacic

Controlled Product

CAS: 444-27-9

Formula: C₄H₇NO₂S

Color and Shape: Neat

Molecular weight: 133.169

Ref: TR-T443735

Thiazolidine-4-carboxylic acid

CAS: 444-27-9

Formula: C₄H₇NO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 133.17

Ref: 10-F231380

Thiazolidine-4-carboxylic acid

CAS: 444-27-9

Formula: C₄H₇NO₂S

Molecular weight: 133.17

Ref: ST-EA-CP-T93004

Timonacic

CAS: 444-27-9

Timonacic is an analog of nicotinamide that has been shown to be an effective inhibitor of energy metabolism in the mitochondria. It has antioxidative properties and can protect against the development of heart disease by inhibiting the production of reactive oxygen species. Timonacic's anti-inflammatory properties may be due to its ability to inhibit prostaglandin synthesis. It also has a high affinity for fatty acids, which may contribute to its inhibitory effects on lipid peroxidation. This drug has a carboxy terminal and is used as a sodium salt, which may play a role in its enzyme inhibition activity. Timonacic inhibits the activities of enzymes such as carnitine acetyltransferase and pyruvate dehydrogenase kinase, which are involved in the biosynthesis of fatty acids. The intramolecular hydrogen bonds formed with timonacic may contribute to its inhibitory effect on these enzymes.

Formula: C₄H₇NO₂S

Purity: Min. 95%

Molecular weight: 133.17 g/mol

Ref: 3D-AAA44427