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CAS 444120-91-6

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6-Chloropyridine-3-boronic acid

Description:
6-Chloropyridine-3-boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a chlorinated pyridine ring. This compound typically exhibits a white to off-white crystalline appearance and is soluble in polar solvents such as water and alcohols, which is a common trait of boronic acids due to their ability to form hydrogen bonds. The presence of the chlorine atom at the 6-position of the pyridine ring influences its reactivity and can enhance its utility in various chemical reactions, particularly in Suzuki coupling reactions, where it serves as a key building block for the synthesis of biaryl compounds. Additionally, the boronic acid group allows for the formation of reversible covalent bonds with diols, making it useful in applications such as drug delivery and sensor technology. Overall, 6-Chloropyridine-3-boronic acid is valued in organic synthesis and medicinal chemistry for its versatile reactivity and functional properties.
Formula:C5H5BClNO2
InChI:InChI=1/C5H5BClNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3,9-10H
SMILES:c1cc(Cl)ncc1B(O)O
Synonyms:
  • Boronic acid, B-(6-chloro-3-pyridinyl)-
  • 2-Chloro-5-pyridineboronic acid
  • (6-Chloropyridin-3-Yl)Boronic Acid
  • 2-Chloropyridine-5-boronic acid
  • 2-Chloro-5-Pyridyl Boronic Acid
  • 6-Chloropyridin-3-Yl-3-Boronic Acid
  • 6-Chloropyridin-3-Ylboronic Acid
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