CAS 444717-23-1

Boc-FLT-Precursor

Description:

Boc-FLT-Precursor, with the CAS number 444717-23-1, is a chemical compound commonly used in the field of medicinal chemistry and peptide synthesis. It is characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group, which is often employed to protect amine functionalities during chemical reactions. The compound is typically utilized in the synthesis of fluorinated peptides, particularly those containing the amino acid phenylalanine (FLT). Its structure allows for selective modifications, facilitating the introduction of fluorine atoms, which can enhance the biological activity or imaging properties of the resulting peptides. The compound is generally stable under standard laboratory conditions but may require specific handling and storage protocols to maintain its integrity. As with many chemical substances, safety precautions should be observed, including the use of appropriate personal protective equipment when handling the compound. Overall, Boc-FLT-Precursor serves as a valuable intermediate in the development of novel therapeutic agents and research tools in biochemistry and pharmacology.

Formula: C₄₂H₄₃N₃O₁₃S

Synonyms:

• 3-N-Boc-5'-O-dimethoxytrityl-3'-O-nosyl-thymidine
• 3-N-BOc-1-[5-O-(4,4'-dimethoxytrityl)-3-O-nitrophenylsolfonyl-2-deoxy-β-D-lyxofuranosyl]thymidine
• 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine
• BOC-FLT
• 3-N-BOC-1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-E-D-LYXOFURANOSYL]THYMIDINE
• 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)- beta-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine
• 1(2H)-Pyrimidinecarboxylic acid, 3-[2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-5-O-(triphenylmethyl)-beta-D-threo-pentofuranosyl]-3,6-dihydro-5-methyl-2,6-dioxo-, 1,1-dimethylethyl ester
• Boc-trytil-nosyl-lyxothymidine, precursor for [18F]FLT
• 1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE
• Boc-trytil-nosyl-lyxothymidine,precursor for [18F]FLT,>95%
• 3-N-Boc-5'-O-dimethoxytrityl-3'-O-nosyl-thymidine 3-N-Boc-1-[5-O-(4,4'-dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-beta-D-lyxofuranosyl]thymidine
• 3-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-beta-D-threo-pentofuranosyl]-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinecarboxylic acid 1,1-dimethylethyl ester

3-N-Boc-5''-O-DMT-3''-O-nosylthymidine

CAS: 444717-23-1

Ref: 7W-GN6748

3-N-Boc-5'-O-DMT-3'-O-Nosyl Thymidine

Controlled Product

CAS: 444717-23-1

Applications 3-N-Boc-5'-O-DMT-3'-O-nosylthymidine (CAS# 444717-23-1) is a useful research chemical compound.

Formula: C₄₂H₄₃N₃O₁₃S

Color and Shape: Neat

Molecular weight: 829.868

Ref: TR-N212160

3-N-Boc-5'-O-DMT-3'-O-nosylthymidine

CAS: 444717-23-1

3-N-Boc-5'-O-DMT-3'-O-nosylthymidine is an anticancer nucleoside that is used as a building block for the synthesis of other anticancer compounds. It can be synthesized by the reaction between 3,4,5′-trimethoxybenzoyl chloride and thymidine in the presence of DMAP and DIPEA. This compound has shown antiviral and anti-inflammatory activities. 3-N-Boc-5'-O-DMT-3'-O-nosylthymidine can also be used as a precursor to synthesize novel nucleosides with different properties. This product is soluble in water, ethanol, acetone, chloroform, benzene, ether or methanol.

Formula: C₄₂H₄₃N₃O₁₃S

Purity: (¹H-Nmr) Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 829.87 g/mol

Ref: 3D-NB09438