CAS 444731-73-1

2,3-Dimethyl-6-nitro-2H-indazole

Description:

2,3-Dimethyl-6-nitro-2H-indazole is a chemical compound characterized by its unique structure, which includes an indazole core substituted with two methyl groups at the 2 and 3 positions and a nitro group at the 6 position. This compound typically exhibits a yellow to orange crystalline appearance. It is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its bioactive properties. The presence of the nitro group can influence its reactivity and solubility, making it a subject of interest in various chemical reactions. Additionally, the methyl substitutions can affect the compound's electronic properties and steric hindrance, which may play a role in its biological activity. As with many nitro-containing compounds, it is essential to handle 2,3-Dimethyl-6-nitro-2H-indazole with care, as nitro groups can be associated with explosive properties under certain conditions. Overall, this compound represents a fascinating area of study in organic and medicinal chemistry.

Formula: C₉H₉N₃O₂

InChI: InChI=1/C9H9N3O2/c1-6-8-4-3-7(12(13)14)5-9(8)10-11(6)2/h3-5H,1-2H3

InChI key: InChIKey=JHGRUPGVUMAQQU-UHFFFAOYSA-N

SMILES: CC1=C2C(C=C(N(=O)=O)C=C2)=NN1C

Synonyms:

• 2,3-Dimethyl-6-nitroindazole
• 2H-indazole, 2,3-dimethyl-6-nitro-
• 2,3-Dimethyl-6-nitro-2H-indazole
• Pazopanib Impurity 19
• 2,3-Dimethyl-6-nitro-1H-i...
• 3-diMethyl-6-nitro-2H-indazole
• 3-Methly-6-nitroindazole
• 2,3-dimethyl-6-nitro-indazole
• 2,3-dimethyl-6-nitro-1H-indazole
• 2,3-dimethyl-6-nitrobazole
• 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE ISO 9001：2015 REACH

2,3-Dimethyl-6-nitro-2H-indazole

CAS: 444731-73-1

Formula: C₉H₉N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 191.1867

Ref: IN-DA0032Y5

2,3-Dimethyl-6-nitro-2H-indazole

CAS: 444731-73-1

2,3-Dimethyl-6-nitro-2H-indazole

Purity: 98%

Molecular weight: 191.19g/mol

Ref: 54-OR350127

Pazopanib Impurity 5

CAS: 444731-73-1

Formula: C₉H₉N₃O₂

Color and Shape: Yellow Solid

Molecular weight: 191.19

Ref: 4Z-P-129010

2,3-Dimethyl-6-nitro-2H-indazole

Controlled Product

CAS: 444731-73-1

Formula: C₉H₉N₃O₂

Color and Shape: Neat

Molecular weight: 191.19

Ref: 86-MM3391.02

Pazopanib Impurity 3

CAS: 444731-73-1

Formula: C₉H₉N₃O₂

Molecular weight: 191.19

Ref: ST-EA-CP-P58018

2,3-Dimethyl-6-nitro-2H-indazole

Controlled Product

CAS: 444731-73-1

Applications 2,3-Dimethyl-6-nitro-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Liu, D. et al.: J. Pharm. Biomed. Anal., 50, 144 (2009); Olaussen, K., et al.: Oncogen., 28, 4249 (2009); Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009); Chan, A., et al.: Drugs, 69, 167 (2009)

Formula: C₉H₉N₃O₂

Color and Shape: Neat

Molecular weight: 191.19

Ref: TR-D471055

2,3-Dimethyl-6-nitro-2H-indazole

CAS: 444731-73-1

Formula: C₉H₉N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 191.19

Ref: 10-F237013