CAS: 4449-51-8 - Cyclopamine

Formula: C₂₇H₄₁NO₂

InChI: InChI=1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17,19-21,23-25,28-29H,6-14H2,1-4H3/t15-,17+,19-,20-,21-,23-,24+,25-,26-,27-/m0/s1

InChI key: InChIKey=QASFUMOKHFSJGL-LAFRSMQTSA-N

SMILES: OC1CC2=CCC3C4C(=C(C)C5(OC6CC(C)CNC6C5C)CC4)CC3C2(C)CC1

Synonyms:

• (2′R,3S,3′R,3′aS,6′S,6aS,6bS,7′aR,11aS,11bR)-1,2,3,3′a,4,4′,5′,6,6′,6a,6b,7,7′,7′a,8,11,11a,11b-Octadecahydro-3′,6′,10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2′(3′H)-furo[3,2-b]pyridin]-3-ol
• (3beta,22S,23R)-17,23-epoxyveratraman-3-ol
• 11-Deoxojervine
• 11-Deoxyjervine
• Hsdb 3505
• Jervine, 11-deoxo-
• Jervine, 11-deoxo- (7CI)
• Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)pyridin)-3-ol, 1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-, (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-
• Spiro[9H-benzo[a]fluorene-9,2′(3′H)-furo[3,2-b]pyridin]-3-ol, 1,2,3,3′a,4,4′,5′,6,6′,6a,6b,7,7′,7′a,8,11,11a,11b-octadecahydro-3′,6′,10,11b-tetramethyl-, (2′R,3S,3′R,3′aS,6′S,6aS,6bS,7′aR,11aS,11bR)-
• Veratraman-3-ol, 17,23-epoxy-, (3-beta,23-beta)- (9CI)
• Veratraman-3-ol, 17,23-epoxy-, (3beta,23beta)-
• Veratraman-3-ol, 17,23-epoxy-, (3β,23β)-

Cyclopamine, 99%

CAS: 4449-51-8

Cyclopamine, is used as a hedgehog [Hh] signaling pathway and Smo inhibitor. It depletes stem-like …

• Formula: C₂₇H₄₁NO₂
• Purity: 99%
• Molecular weight: 411.62

CYCLOPAMINE

CAS: 4449-51-8

• Formula: C₂₇H₄₁NO₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 411.6199

Cyclopamine

CAS: 4449-51-8

• Formula: C₂₇H₄₁NO₂
• Purity: >99%
• Molecular weight: 411.63

Cyclopamine

CAS: 4449-51-8

• Formula: C₂₇H₄₁NO₂
• Molecular weight: 411.63

Cyclopamine

CAS: 4449-51-8

• Formula: C₂₇H₄₁NO₂
• Purity: ≥ 98.0%
• Color and Shape: White to off-white solid
• Molecular weight: 411.6

Cyclopamine

CAS: 4449-51-8

• Color and Shape: White Powder
• Molecular weight: 411.62g/mol

Cyclopamine

CAS: 4449-51-8

Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the …

• Formula: C₂₇H₄₁NO₂
• Purity: 98.31% - 99.66%
• Color and Shape: White Crystalline Solid
• Molecular weight: 411.62

Cyclopamine

CAS: 4449-51-8

Natural alkaloid

• Formula: C₂₇H₄₁NO₂
• Purity: ≥ 95.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 411.63

Cyclopamine

CAS: 4449-51-8

M01634 - Cyclopamine

• Formula: C₂₇H₄₁NO₂
• Purity: >98%
• Color and Shape: Solid
• Molecular weight: 411.6300048828125

Cyclopamine

CAS: 4449-51-8

• Formula: C₂₇H₄₁NO₂
• Color and Shape: Off-White
• Molecular weight: 411.62

Cyclopamine

CAS: 4449-51-8

Inhibitor of the Smoothened receptor and Hedgehog signalling pathway. Cyclopamine is a steroidal alkaloid that …

• Formula: C₂₇H₄₁NO₂
• Purity: Min. 95%
• Color and Shape: White Solid
• Molecular weight: 411.31373