CAS 444912-48-5

(2-Iodo-5-nitrophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone

Description:

The chemical substance known as (2-Iodo-5-nitrophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone, with the CAS number 444912-48-5, is a complex organic compound characterized by its multi-functional groups. It features an indole core, which is a bicyclic structure known for its presence in many biologically active compounds. The presence of a nitro group and an iodo substituent on the phenyl ring contributes to its reactivity and potential applications in medicinal chemistry. The piperidine moiety adds to its structural diversity, potentially influencing its pharmacological properties. This compound may exhibit various biological activities, making it of interest in drug discovery and development. Its molecular structure suggests potential interactions with biological targets, which could be explored in therapeutic contexts. As with many synthetic organic compounds, its stability, solubility, and reactivity would depend on the specific conditions under which it is handled. Safety and handling precautions are essential due to the presence of halogen and nitro groups, which can impart toxicity or environmental concerns.

Formula: C₂₂H₂₂IN₃O₃

InChI: InChI=1S/C22H22IN3O3/c1-24-11-5-4-6-16(24)13-25-14-19(17-7-2-3-8-21(17)25)22(27)18-12-15(26(28)29)9-10-20(18)23/h2-3,7-10,12,14,16H,4-6,11,13H2,1H3

InChI key: InChIKey=ZUHIXXCLLBMBDW-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=2C(N(CC3N(C)CCCC3)C1)=CC=CC2)C4=CC(N(=O)=O)=CC=C4I

Synonyms:

• (2-Iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone
• (2-Iodo-5-nitrophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone
• 1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodo-5-nitrobenzoyl)-1H-indole
• Am 1241
• methanone, (2-iodo-5-nitrophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-

(R,S)-AM1241

CAS: 444912-48-5

Formula: C₂₂H₂₂IN₃O₃

Molecular weight: 503.33

Ref: 7W-GL6144

AM1241

CAS: 444912-48-5

AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.

Formula: C₂₂H₂₂IN₃O₃

Purity: 98.937% - 99.1%

Color and Shape: Solid

Molecular weight: 503.33

Ref: TM-T6755

AM-1241

Controlled Product

CAS: 444912-48-5

AM-1241 is a cannabinoid receptor 2 agonist that inhibits the growth of cancer cells. It has been shown to inhibit cell proliferation and induce apoptosis in human glioblastoma cell lines. AM-1241 also inhibits the production of proteins that are associated with tumorigenesis, such as cyclin D1, cyclin E, Bcl-2, and survivin. AM-1241 is currently being investigated for its potential use in cancer treatment.

Purity: Min. 95%

Ref: 3D-CA175168

(2-Iodo-5-nitrophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone-d5

Controlled Product

CAS: 444912-48-5

Formula: C₂₂D₅H₁₇IN₃O₃

Color and Shape: Neat

Molecular weight: 508.364

Ref: TR-I715702

(2-Iodo-5-nitrophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone

Controlled Product

CAS: 444912-48-5

Formula: C₂₂H₂₂IN₃O₃

Color and Shape: Neat

Molecular weight: 503.333

Ref: TR-I715700