CAS 444912-53-2

(2-Iodo-5-nitrophenyl)[1-[[(2S)-1-methyl-2-piperidinyl]methyl]-1H-indol-3-yl]methanone

Description:

The chemical substance known as (2-Iodo-5-nitrophenyl)[1-[[(2S)-1-methyl-2-piperidinyl]methyl]-1H-indol-3-yl]methanone, with the CAS number 444912-53-2, is a complex organic compound characterized by its multi-functional groups. It features an indole moiety, which is a bicyclic structure known for its presence in many biologically active compounds. The presence of a piperidine ring contributes to its potential pharmacological properties, as piperidine derivatives are often associated with various biological activities. The iodo and nitro substituents on the phenyl ring enhance the compound's reactivity and may influence its interaction with biological targets. This compound is likely to exhibit lipophilicity due to its aromatic and aliphatic components, which can affect its solubility and permeability in biological systems. Additionally, the stereochemistry indicated by the (2S) configuration suggests specific spatial arrangements that could be crucial for its biological activity. Overall, this compound may have applications in medicinal chemistry, particularly in the development of new therapeutic agents.

Formula: C₂₂H₂₂IN₃O₃

InChI: InChI=1S/C22H22IN3O3/c1-24-11-5-4-6-16(24)13-25-14-19(17-7-2-3-8-21(17)25)22(27)18-12-15(26(28)29)9-10-20(18)23/h2-3,7-10,12,14,16H,4-6,11,13H2,1H3/t16-/m0/s1

InChI key: InChIKey=ZUHIXXCLLBMBDW-INIZCTEOSA-N

SMILES: C(=O)(C=1C=2C(N(C[C@H]3N(C)CCCC3)C1)=CC=CC2)C4=CC(N(=O)=O)=CC=C4I

Synonyms:

• (2-Iodo-5-nitrophenyl)[1-[[(2S)-1-methyl-2-piperidinyl]methyl]-1H-indol-3-yl]methanone
• (S)-(-)-1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodo-5-nitrobenzoyl)-1H-indole
• Methanone, (2-iodo-5-nitrophenyl)[1-[[(2S)-1-methyl-2-piperidinyl]methyl]-1H-indol-3-yl]-

(S)-(-)-1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodo-5-nitrobenzoyl)-1H-indole(S)-AM1241

Controlled Product

CAS: 444912-53-2

Formula: C₂₂H₂₂IN₃O₃

Color and Shape: Neat

Molecular weight: 503.333

Ref: TR-M725618

(2-Iodo-5-nitrophenyl)(1-(((2S)-1-methyl-2-piperidinyl)methyl)-1H-indol-3-yl)-methanone

Controlled Product

CAS: 444912-53-2

(2-Iodo-5-nitrophenyl)(1-(((2S)-1-methyl-2-piperidinyl)methyl)-1H-indol-3-yl)-methanone (SNJ14) is a synthetic cannabinoid that has been shown to be effective in animal models as an analgesic and as a stimulator of the cb2 receptor. SNJ14 is also an antagonist at the opioid receptor, which leads to its antinociceptive properties. This drug has been shown to have cytotoxic effects on cancer cells and has been studied for use in chemotherapy treatments. SNJ14 has also been shown to be effective in treating neuropathic pain.

Formula: C₂₂H₂₂IN₃O₃

Purity: Min. 95%

Molecular weight: 503.3 g/mol

Ref: 3D-USA91253

(S)-AM1241

CAS: 444912-53-2

(S)-AM1241: Agonist for CB2 receptor; stronger for humans (EC50 = 131 nM) than rats/mice. Antinociceptive to thermal pain; blocked by CB2 inhibitor SR 144528.

Formula: C₂₂H₂₂IN₃O₃

Color and Shape: Solid

Molecular weight: 503.33

Ref: TM-T38147