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CAS 444930-42-1

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PCNA-I1

Description:
PCNA-I1, with the CAS number 444930-42-1, is a chemical compound that functions primarily as a selective inhibitor of the proliferating cell nuclear antigen (PCNA). This compound is notable for its role in cancer research, particularly in studies focused on cell proliferation and DNA repair mechanisms. PCNA itself is a crucial protein that assists in DNA replication and repair, making it a significant target for therapeutic intervention in cancer treatment. PCNA-I1 exhibits characteristics typical of small molecule inhibitors, including the ability to bind to the target protein and disrupt its function, thereby influencing cellular processes. Its efficacy and specificity make it a valuable tool in biochemical assays and potential drug development. Additionally, the compound's solubility, stability, and bioavailability are important factors that determine its applicability in research and clinical settings. As with many chemical substances, safety data and handling precautions should be reviewed prior to use, as they can vary based on the compound's properties and intended applications.
Formula:C17H14N2O2S
Synonyms:
  • N-(3-Methylthiophene-2-carboxylic acid)-N'-[(1-hydroxy-2-naphthalenyl)methylene]hydrazide
  • 2-Thiophenecarboxylic acid, 3-methyl-, 2-[(1-hydroxy-2-naphthalenyl)methylene]hydrazide
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Found 3 products.
  • PCNA-I1
    Apollo Scientific
    + Info

    PCNA-I1

    CAS:
    <p>PCNA-I1</p>
    Purity:≥95%
    Molecular weight:310.37g/mol

    Ref: 54-BUP03605

    1mg
    124.00€
    5mg
    271.00€
    10mg
    424.00€
    25mg
    690.00€
    50mg
    971.00€
    100mg
    1,288.00€
  • PCNA-I1
    Targetmol
    + Info

    PCNA-I1

    CAS:
    <p>PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.</p>
    Formula:C17H14N2O2S
    Purity:97.64%
    Color and Shape:Solid
    Molecular weight:310.37

    Ref: TM-T8955

  • PCNA I1
    Biosynth
    + Info

    PCNA I1

    CAS:
    <p>PCNA I1 is a trimeric protein that is composed of three identical subunits. It is a component of the DNA replication machinery and plays an important role in the regulation of DNA synthesis, cell growth, and tumorigenesis. PCNA I1 has been shown to have inhibitory effects on tumor cells by stabilizing DNA replication and inhibiting tumor cell proliferation. It also inhibits tumor cell autophagy. The validation and inhibition of tumor cells by PCNA I1 has been confirmed in vitro with mouse models.</p>
    Formula:C17H14N2O2S
    Purity:Min. 95%
    Molecular weight:310.4 g/mol

    Ref: 3D-USA93042

    50mg
    917.00€
    100mg
    1,203.00€