CAS 445-03-4

2-Trifluoromethyl-4-chloroaniline

Description:

2-Trifluoromethyl-4-chloroaniline, with the CAS number 445-03-4, is an organic compound that belongs to the class of anilines, which are characterized by the presence of an amino group (-NH2) attached to an aromatic ring. This particular compound features a trifluoromethyl group (-CF3) and a chloro group (-Cl) on the aromatic ring, specifically at the 2 and 4 positions, respectively. The presence of these electronegative substituents significantly influences its chemical properties, including increased lipophilicity and potential reactivity in electrophilic substitution reactions. It is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. The compound is of interest in various fields, including pharmaceuticals and agrochemicals, due to its potential applications in the synthesis of biologically active molecules. Safety precautions should be observed when handling this compound, as it may pose health risks, including toxicity and environmental hazards. Proper storage and disposal methods are essential to mitigate any potential risks associated with its use.

Formula: C₇H₅ClF₃N

InChI: InChI=1S/C7H5ClF3N/c8-4-1-2-6(12)5(3-4)7(9,10)11/h1-3H,12H2

InChI key: InChIKey=CVINWVPRKDIGLL-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=C(N)C=CC(Cl)=C1

Synonyms:

• 1-Amino-4-chloro-2-trifluoromethylbenzene
• 2-Trifluoromethyl-4-chloroaniline
• 4-Chloro-2-(trifluoromethyl)aniline
• 4-Chloro-2-(trifluoromethyl)benzenamine
• 4-Chloro-alpha,alpha,alpha-trifluoro-o-toluidine
• 4-Chloro-α,α,α-trifluoro-o-toluidine
• 5-Chloro-2-Amino Benzotrifluoride
• 5-Chloro-2-aminobenzotrifluoride
• 5-Chloro-2-aminotrifluorotoluene
• Benzenamine, 4-chloro-2-(trifluoromethyl)-
• Diazo Fast Scarlet VD
• Fast Scarlet Salt VD
• Fast Scarlet VD Salt
• Scarlet Salt NVD
• o-Toluidine, 4-chloro-α,α,α-trifluoro-
• C.I. Azoic Diazo Component 17

2-Amino-5-chlorobenzotrifluoride

CAS: 445-03-4

Formula: C₇H₅ClF₃N

Purity: >98.0%(GC)

Color and Shape: Colorless to Orange to Green clear liquid

Molecular weight: 195.57

Ref: 3B-A1058

4-Chloro-2-(trifluoromethyl)aniline, 97%

CAS: 445-03-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₅ClF₃N

Purity: 97%

Color and Shape: Liquid, Clear colorless to yellow to brown

Molecular weight: 195.57

Ref: 02-B21755

4-Chloro-2-(trifluoromethyl)aniline

CAS: 445-03-4

Formula: C₇H₅ClF₃N

Purity: 97%

Color and Shape: Liquid

Molecular weight: 195.5695

Ref: IN-DA003L2C

2-Amino-5-chlorobenzotrifluoride

CAS: 445-03-4

2-Amino-5-chlorobenzotrifluoride

Formula: C₇H₅ClF₃N

Purity: 99%

Color and Shape: clear. very dark yellow liquid

Molecular weight: 195.57g/mol

Ref: 54-PC1050

2-Amino-5-chlorobenzotrifluoride

CAS: 445-03-4

Formula: C₇H₅ClF₃N

Molecular weight: 195.57

Ref: 7W-GK2511

2-Trifluoromethyl-4-chloroaniline

CAS: 445-03-4

Formula: C₇H₅ClF₃N

Color and Shape: Neat

Molecular weight: 195.57

Ref: 04-C17845300

2-Amino-5-chlorobenzotrifluoride

CAS: 445-03-4

Formula: C₇H₅ClF₃N

Purity: 97%

Color and Shape: Clear

Molecular weight: 195.57

Ref: 10-F002680

2-Amino-5-chlorobenzotrifluoride

Controlled Product

CAS: 445-03-4

Formula: C₇H₅ClF₃N

Color and Shape: Neat

Molecular weight: 195.57

Ref: TR-A445035

4-Chloro-2-(trifluoromethyl)aniline

CAS: 445-03-4

4-Chloro-2-(trifluoromethyl)aniline (4C-TFAA) is a carbonyl reductant that can reduce the C=O group to the corresponding alcohol. 4C-TFAA is an effective inhibitor of the reaction between oxalyl and chloride, and has been shown to be capable of inhibiting β-unsaturated ketones. It can also be used in non-nucleoside inhibitors, such as an acylation reaction with hydrochloric acid and copper chloride. 4C-TFAA is synthesized by reacting copper with acetic anhydride, followed by chlorination with phosphorus pentachloride.

Formula: C₇H₅ClF₃N

Purity: Min. 95%

Molecular weight: 195.57 g/mol

Ref: 3D-FC64327